G3BP2
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Official Full Name
GTPase activating protein (SH3 domain) binding protein 2 -
Overview
Probable scaffold protein that may be involved in mRNA transport. -
Synonyms
G3BP2;GTPase activating protein (SH3 domain) binding protein 2;ras GTPase-activating protein-binding protein 2;KIAA0660;Ras GTPase activating protein SH3 domain binding protein 2;G3BP-2;GAP SH3 domain-binding protein 2;Ras-GTPase activating protein
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
G3BP2 involved in several pathways and played different roles in them. We selected most pathways G3BP2 participated on our site, such as TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with G3BP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TNF-alpha/NF-kB Signaling Pathway | SMARCE1,NKIRAS2,DCAF7,CAPN3,MCC,MARK2,ZFAND5,PDCD2,PAPOLA,RNF25 |
Protein Function
G3BP2 has several biochemical functions, for example, nucleotide binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by G3BP2 itself. We selected most functions G3BP2 had, and list some proteins which have the same functions with G3BP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide binding | ADCY2B,EIF4B,SRSF11,CTPS1A,U2AF1L4,HNRNPH3,RBM24B,LARP7,RBMY1B,STK24B |
| protein binding | MUL1,TMEM203,TMIGD2,HIST1H2BF,USP36,CCDC92,SPINK2,RGS1,GTF2A2,SIK3 |
| poly(A) RNA binding | DDX54,DDX47,FBL,ZRANB2,DDX23,SUPV3L1,RPL26,SUPT5H,TIA1,HIST4H4 |
| receptor signaling complex scaffold activity | CD3G,SPAG9,LRRK2,ROPN1B,SPAG9A,RGS14,MAGI2,GRIP2A,DEDD2,MMS19 |
Interacting Protein
G3BP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with G3BP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of G3BP2.
USP10;EIF1B;FARS2;ABL1;RNH1;NUP214;NUP62;DDX10;GNL2;UBAP2;C3orf17;RPL22L1;NUFIP2;ASCC3;WDR36;ATXN2L
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References
- Peluso, JJ; Griffin, D; et al. Progesterone Receptor Membrane Component-1 (PGRMC1) and PGRMC-2 Interact to Suppress Entry into the Cell Cycle in Spontaneously Immortalized Rat Granulosa Cells. BIOLOGY OF REPRODUCTION 91:-(2014).
- Bidet, K; Dadlani, D; et al. G3BP1, G3BP2 and CAPRIN1 Are Required for Translation of Interferon Stimulated mRNAs and Are Targeted by a Dengue Virus Non-coding RNA. PLOS PATHOGENS 10:-(2014).
