G2E3
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Official Full Name
G2/M-phase specific E3 ubiquitin protein ligase -
Overview
G2/M phase-specific E3 ubiquitin-protein ligase is an enzyme that in humans is encoded by the G2E3 gene. -
Synonyms
G2E3;G2/M-phase specific E3 ubiquitin protein ligase;KIAA1333;G2/M phase-specific E3 ubiquitin-protein ligase;FLJ20333;PHD finger protein 7B;PHF7B;G2/M phase specific E3 ubiquitin protein ligase;G2/M-phase specific E3 ubiquitin ligase
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Chicken
- Cynomolgus
- Mouse
- Mammalian Cell
- HEK293
- His
- His&Fc&Avi
Involved Pathway
G2E3 involved in several pathways and played different roles in them. We selected most pathways G2E3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with G2E3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
G2E3 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by G2E3 itself. We selected most functions G2E3 had, and list some proteins which have the same functions with G2E3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| coenzyme F420-0 gamma-glutamyl ligase activity | ITCHA,MYLIPA,MARCH11,ARIH1L,TMEM129,HERC2,RNF169,RNF149,RC3H2,HECW2 |
| metal ion binding | CTCFL,FREM1,ZFP143,CMC1,PFKMA,DHX57,RTCB,CRYABA,PRPSAP2,HDAC8 |
| protein-glycine ligase activity, initiating | DTX1,MYLIPB,MARCH5L,TRIM50,RNF169,MGRN1A,RFWD2,TRIM71,RNF180,UBE2IB |
| ubiquitin protein ligase activity | RBX1,UBE2G1,PARK2,BTRC,UBE2B,ANKIB1,ZNRF2,RNF126,HECW2,TRIM72 |
| protein-glycine ligase activity | TRIM71,RNF144AA,ZNRF2B,MGRN1A,RNF149,MARCH5L,ZNRF3,LTN1,RNF187,HECW2 |
| protein-glycine ligase activity, elongating | RFWD2,MARCH5L,MYLIPA,MYLIPB,ARIH1L,DTX1,TRIM50,RNF144AA,HERC2,MARCH6 |
| protein-glutamic acid ligase activity | NEURL1B,MARCH11,TRIM41,ZNRF3,MYLIPB,MARCH6,RNF187,MGRN1A,RNF180,ZNRF2B |
| ribosomal S6-glutamic acid ligase activity | UBE2M,MUL1A,DTX1,TRIM41,TRIM71,NEURL3,HERC2,NEURL1B,SIAH2L,ZNRF3 |
| coenzyme F420-2 alpha-glutamyl ligase activity | MARCH4,HECW2,NEURL3,MUL1A,RNF187,NEURL1B,RFWD2,RAG1,RC3H2,DTX1 |
Interacting Protein
G2E3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with G2E3 here. Most of them are supplied by our site. Hope this information will be useful for your research of G2E3.
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References
- Cuchet, D; Ferrera, R; et al. Characterization of antiproliferative and cytotoxic properties of the HSV-1 immediate-early ICPo protein. JOURNAL OF GENE MEDICINE 7:1187-1199(2005).
