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FZD9

  • Official Full Name

    frizzled family receptor 9

  • Overview

    Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype.FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.

  • Synonyms

    FZD9;frizzled family receptor 9;frizzled (Drosophila) homolog 9 , frizzled 9, seven transmembrane spanning receptor , frizzled homolog 9 (Drosophila);frizzled-9;CD349;FZD3;fz-9;fzE6;hFz9;frizzled homolog 9;frizzled 9, seven transmembrane spann

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • Mouse
  • Mus musculus
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • E.coli expression system
  • GST
  • His
  • Non
  • Fc
  • hIgG4
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
FZD9-13071H Recombinant Human FZD9, GST-tagged E.coli Human GST 22-246a.a.
FZD9-3809H Recombinant Human FZD9 protein, His-tagged E.coli Human His 23-247 aa
FZD9-1767R Recombinant Rhesus Monkey FZD9 Protein HEK293 Rhesus macaque Non 23-229 a.a.
FZD9-1768R Recombinant Rhesus Monkey FZD9 Protein, hIgG1-tagged HEK293 Rhesus macaque Fc 23-229 a.a.
FZD9-1769R Recombinant Rhesus Monkey FZD9 Protein, hIgG4-tagged HEK293 Rhesus macaque hIgG4 23-229 a.a.
FZD9-4701C Recombinant Chicken FZD9 Mammalian Cell Chicken His
FZD9-6123M Recombinant Mouse FZD9 Protein Mammalian Cell Mouse His
FZD9-1138H Recombinant Human FZD9 Protein (Leu23-Ala247), N-His tagged E.coli Human His Leu23-Ala247
FZD9-148H Recombinant Human FZD9 Protein, C-His-tagged E.coli Human His
FZD9-1541H Recombinant Human FZD9 Protein, His-tagged E.coli Human His Leu23-Asp229
FZD9-3412M Recombinant Mouse FZD9 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
FZD9-3412M-B Recombinant Mouse FZD9 Protein Pre-coupled Magnetic Beads HEK293 Mouse
FZD9-5202H Recombinant Human FZD9 Protein (Met1-Asp185), C-Fc tagged Mammalian cells Human Fc Met1-Asp185
RFL16491GF Recombinant Full Length Chicken Frizzled-9(Fzd9) Protein, His-Tagged E.coli expression system Chicken His Full L. Full Length (1-392)
RFL21633MF Recombinant Full Length Mouse Frizzled-9(Fzd9) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length of Mature Protein (24-592)
RFL8653HF Recombinant Full Length Human Frizzled-9(Fzd9) Protein, His-Tagged E.coli expression system Human His Full L. Full Length of Mature Protein (23-591)

    Involved Pathway

    FZD9 involved in several pathways and played different roles in them. We selected most pathways FZD9 participated on our site, such as Wnt signaling pathway,Hippo signaling pathway,Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway CAMK2G1,WNT4A,WNT1,FRAT2,MYCB,Fzd4,TBL1XR1,PRKACBB,FZD9B,ROCK2
    HTLV-I infection CDC20,CD3D,SLC25A5,PPP3R1,ATF3,DLG1,POLE3,TCF3,TGFB1,APC2
    Hippo signaling pathway TCF7L2,CTGF,GDF7,CRB2,AREG,DVL3,GLI2,TGFB1,BIRC5,SNAI2
    Pathways in cancer GNG7,STAT5A,FASLG,CBL,RB1,AKT2,PTGER3,STAT1,SFPI1,ETS1
    Signaling pathways regulating pluripotency of stem cells AKT1,PIK3CD,AXIN2,WNT2B,ID3,ZIC3,GRB2,MAPK3,TBX3,MAP2K2
    Melanogenesis RAF1A,POMC,GNA15.4,Kitl,FZD3A,WNT7B,PLCB2,KIT,FZD3,MC1R
    Basal cell carcinoma GSK3B,WNT16,WNT9A,DVL3,APC2,HHIP,FZD7,WNT2B,WNT7B,WNT3
    Proteoglycans in cancer PRKACA,ACTG1,WNT10B,GPC3,AKT1,ARHGEF1,PLCG1,MAPK11,BRAF,PPP1CC

    Protein Function

    FZD9 has several biochemical functions, for example, G-protein coupled receptor activity,Wnt-activated receptor activity,Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD9 itself. We selected most functions FZD9 had, and list some proteins which have the same functions with FZD9. You can find most of the proteins on our site.

    Function Related Protein
    protein homodimerization activity CHMP4A,SNX1,C9orf142,NDP,GDF7,PYGB,GNPTG,TFAP2E,CSF1,HLCS
    protein heterodimerization activity IL12A,NR4A2,SMC4,NTSR1,ADD1,AHR,HIST1H3F,LTC4S,HNF1B,SPNA1
    G-protein coupled receptor activity PROKR1A,KISS1RB,ADRA2DB,ADRB3A,VIPR2,TAS1R2.1,OXTRL,GPR27,CCR10,GPR52
    Wnt-activated receptor activity FZD7A,FZD7B,FZD2,FZD3,FZD8B,FZD10,FZD1,FZD9B,FZD5,FZD3B
    Wnt-protein binding LRP5L,LRP6,CTHRC1,SMO,FZD7,WLS,SFRP1,LRP2A,FZD6,SFRP2

    Interacting Protein

    FZD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD9.

    FZD9 Related Signal Pathway

    Resources

    Research Area

    Frizzled Receptors
    Wnt Receptors
    Neural Stem Cell Markers

    References

    • Wang, HX; Tekpetey, FR; et al. Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells. MOLECULAR HUMAN REPRODUCTION 15:11-17(2009).
    • Battula, VL; Treml, S; et al. Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody. DIFFERENTIATION 76:326-336(2008).
    • Zhang, Z; Schittenhelm, J; et al. Upregulation of frizzled 9 in astrocytomas. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 32:615-624(2006).

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