FZD5
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Official Full Name
frizzled family receptor 5 -
Overview
Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD5 protein is believed to be the receptor for the Wnt5A ligand. -
Synonyms
FZD5;frizzled family receptor 5;C2orf31, chromosome 2 open reading frame 31 , frizzled (Drosophila) homolog 5 , frizzled 5, seven transmembrane spanning receptor , frizzled homolog 5 (Drosophila);frizzled-5;DKFZP434E2135;HFZ5;fz-5;fzE5;Wnt rec
Recombinant Proteins
- Human
- Rat
- Mouse
- Zebrafish
- Xenopus laevis
- Mus musculus
- E.coli
- Human Cell
- Mammalian cells
- CHO
- HEK293
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- E.coli expression system
- His
- His&Fc
- Fc
- Non
- His&Flag
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FZD5-13068H | Recombinant Human FZD5, His-tagged | E.coli | Human | His | C-term-62a.a. | |
| FZD5-713H | Recombinant Human FZD5, Fc-His tagged | Human Cell | Human | His&Fc | 1-167 a.a. | |
| FZD5-244H |
Active Recombinant Human FZD5, Fc Chimera
|
Mammalian cells | Human | Fc |
|
|
| FZD5-536H |
Active Recombinant Human FZD5 Protein, Fc Chimera
|
CHO | Human | Fc |
|
|
| FZD5-167H | Recombinant Human FZD5 protein, Fc-tagged | HEK293 | Human | Fc | Ala27-Pro167 |
|
| FZD5-2431R | Recombinant Rat FZD5 Protein | Mammalian Cell | Rat | His |
|
|
| FZD5-3173H | Recombinant Human FZD5 protein, His-tagged | HEK293 | Human | His | Met1-Pro167 |
|
| Fzd5-8681M | Recombinant Mouse Fzd5, Fc tagged | CHO | Mouse | His | 1-167 a.a. |
|
| FZD5-8754Z | Recombinant Zebrafish FZD5 | Mammalian Cell | Zebrafish | His |
|
|
| FZD5-001MCL | Recombinant Mouse FZD5 cell lysate | CHO | Mouse | Non |
|
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| FZD5-2388HCL | Recombinant Human FZD5 cell lysate | Human Cell | Human | Non |
|
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| FZD5-1112HFL | Recombinant Human FZD5 protein, His&Flag-tagged | HEK293 | Human | His&Flag | 1-585 aa |
|
| FZD5-1280M | Recombinant Mouse FZD5 protein(Met1-Pro167), hFc-tagged | CHO | Mouse | Fc | Met1-Pro167 |
|
| FZD5-1438H | Recombinant Human FZD5 protein, Fc-tagged | HEK293 | Human | Fc | 27-167 a.a. |
|
| FZD5-189H | Recombinant Human FZD5 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
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| FZD5-189H-B | Recombinant Human FZD5 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
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| FZD5-2087R | Recombinant Rat FZD5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
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| FZD5-2087R-B | Recombinant Rat FZD5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
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| FZD5-257H | Recombinant Human FZD5 Protein, Fc-tagged | HEK293 | Human | Fc | 585 |
|
| FZD5-4595H | Recombinant Human FZD5 Protein, GST-tagged | Wheat Germ | Human | GST |
|
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| FZD5-5085HF | Recombinant Full Length Human FZD5 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 585 amino acids |
|
| RFL19746XF | Recombinant Full Length Xenopus Laevis Frizzled-5(Fzd5) Protein, His-Tagged | E.coli expression system | Xenopus laevis | His | Full L. Full Length of Mature Protein (27-559) |
|
| RFL27056HF | Recombinant Full Length Human Frizzled-5(Fzd5) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length of Mature Protein (27-585) |
|
| RFL32401RF | Recombinant Full Length Rat Frizzled-5(Fzd5) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length of Mature Protein (27-585) |
|
| RFL8244MF | Recombinant Full Length Mouse Frizzled-5(Fzd5) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (27-585) |
|
Involved Pathway
FZD5 involved in several pathways and played different roles in them. We selected most pathways FZD5 participated on our site, such as Wnt signaling pathway,Hippo signaling pathway,Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | SFRP1,FZD1,PPARD,BAMBI,MMP7,WNT2,PRICKLE1A,CAMK2G1,EP300,RHOAD |
| Proteoglycans in cancer | PRKACG,PTPN6,PIK3CA,FZD1,MDM2,AKT2,FAS,TIMP3,HIF1A,PIK3R5 |
| Melanogenesis | EDNRB2,PRKACA,PRKACBA,WNT8B,GNAQ,GNA11A,ASIP,CREB3L3L,CAMK2B1,TCF7L1A |
| HTLV-I infection | POLB,HLA-DPB1,PIK3CA,CD3D,MAPK8,DVL2,CRTC1,KRAS,RANBP1,CRTC3 |
| Signaling pathways regulating pluripotency of stem cells | HOXB1,MAP2K1,FGFR1,SMAD2,WNT8A,HAND1,ACVR1,AKT2,STAT3,ACVR1C |
| Hippo signaling pathway | WNT2,PPP2R2A,NF2,WNT4,TP73,PPP1CB,ID2,SNAI2,TGFB2,STK3 |
| Pathways in cancer | WNT8A,FGF13,LAMA2,CASP9,MLH1,RELA,STK4,PGF,BAX,MSH3 |
| Basal cell carcinoma | BMP4,WNT3A,FZD8,TCF7L2,FZD2,WNT8A,BMP2,GLI3,STK36,TRP53 |
Protein Function
FZD5 has several biochemical functions, for example, G-protein coupled receptor activity,Wnt-activated receptor activity,Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD5 itself. We selected most functions FZD5 had, and list some proteins which have the same functions with FZD5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Wnt-protein binding | ROR1,LRP5,FZD6,SZL,SFRP1,FZD9,GM12824,SETD6,SFRP4,FZD3B |
| protein binding | ANKFY1,SPATA24,ZNF792,SERPINA1,IGF2BP2,BARD1,ZBTB2,CHAF1A,ANKS4B,CCT5 |
| protein kinase binding | PRKRIP1,CDH2,PTPN6,PTPN2,TPX2,NBEA,GSTP2,PIH1D1,RPS19,CD226 |
| G-protein coupled receptor activity | TMTOPSA,OPN4B,CALCRLA,FPR3,GPR32,OLFR494,TRHR2,GPR132B,OR2AP1,F2RL1.2 |
| ubiquitin protein ligase binding | USP2,HDAC6,USP13,JAK1,TANK,MAP1LC3C,SMAD2,ASB4,CASP10,UBE2G2 |
| Wnt-activated receptor activity | LRP2A,LRP5,FZD2,FZD8,FZD8A,FZD9,FZD9B,FZD3,FZD1,FZD6 |
Interacting Protein
FZD5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD5 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD5.
SCYL2;WNT5A;BAMBI;WNT2B;RGS2;GSK3B;ABI3BP;UBTD1;LZTFL1;RPS6KA6;LRRK2
FZD5 Related Signal Pathway
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