FUZ

  • Official Full Name

    fuzzy homolog
  • Synonyms

    FUZ;fuzzy homolog (Drosophila);protein fuzzy homolog;FLJ22688;Fy

Recombinant Proteins

  • Rat
  • Human
  • Mouse
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
FUZ-2417R Recombinant Rat FUZ Protein Mammalian Cells Rat His
FUZ-6110HCL Recombinant Human FUZ 293 Cell Lysate HEK293 Human Non
FUZ-2073R Recombinant Rat FUZ Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
FUZ-2073R-B Recombinant Rat FUZ Protein Pre-coupled Magnetic Beads HEK293 Rat
Fuz-3111M Recombinant Mouse Fuz Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
FUZ-4571H Recombinant Human FUZ Protein, GST-tagged Wheat Germ Human GST
FUZ-5236HF Recombinant Full Length Human FUZ Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 418 amino acids

    Involved Pathway

    FUZ involved in several pathways and played different roles in them. We selected most pathways FUZ participated on our site, such as DNA Double-Strand Break Repair,DNA Repair,Fanconi Anemia Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUZ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) RNF168,BABAM1,KIAA0146,RHNO1,PPP4CA,TP53BP1,RAD1,PPP4R2,TOPBP1,PPP4R2B
    Homology Directed Repair PPP4CA,KIAA0146,TOPBP1,RNF4,RHNO1,PPP4CB,EME1,TIMELESS,RAD51AP1,GEN1
    Fanconi Anemia Pathway POLN,FANCI,MLH1,RMI2,FANCL,REV3L,FANCG,USP1,FANCF,FANCB
    HDR through Homologous Recombination (HRR) RAD9,RTEL1,RAD9B,TOPBP1,GEN1,RBBP8,HUS1,RHNO1,KIAA0146,RAD51AP1
    DNA Double-Strand Break Repair TDP2B,TDP1,PPP4R2B,RAD9B,HTATIP,TDP2,RTEL1,KIAA0146,RAD50,BAZ1B
    Homologous recombination BRCA2,SYCP3,CDK5R2,RAD51D,MRE11A,RAD51,SSBP1,RAD51L1,NBN,RPA4
    DNA Repair TP53BP1,RTEL1,RAD9,COPS2,ALKBH3,CLSPN,INO80E,MAD2L2,ZBTB32,WRN

    Protein Function

    FUZ has several biochemical functions, for example, 3-flap endonuclease activity,DNA binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FUZ itself. We selected most functions FUZ had, and list some proteins which have the same functions with FUZ. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding MTF1,HOXB13A,NFE2L1A,HOXD4A,ZKSCAN3,RHOXF1,TBPL2,ERCC3,RYBPA,ZFP507
    metal ion binding KCNIP1B,MT1X,PPARG,MT2,ACACB,ASAP2,CLCNKB,ZDHHC6,ZMYND12,TRIM30A
    protein binding HSPA1L,TMEM8B,MTMR9,F10,TMEM88,RIPK4,FOXR1,TNP1,POLL,KRTAP10-5
    3-flap endonuclease activity MUS81

    Interacting Protein

    FUZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUZ here. Most of them are supplied by our site. Hope this information will be useful for your research of FUZ.

    RSG1

    Resources

    References

    • Brooks, ER; Wallingford, JB; et al. Multiciliated Cells. CURRENT BIOLOGY 24:R973-R982(2014).
    • Tabler, JM; Barrell, WB; et al. Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF related syndromes. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:1888-1888(2014).

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