FRAP1
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Official Full Name
MTOR mechanistic target of rapamycin (serine/threonine kinase) -
Overview
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. -
Synonyms
FRAP;FRAP1;FRAP2;RAFT1;RAPT1;FLJ44809;serine/threonine-protein kinase mTOR;OTTHUMP00000001983;rapamycin target protein 1;mammalian target of rapamycin;rapamycin and FKBP12 target 1;FKBP-rapamycin associated protein;rapamycin associated protein FRAP2;FKBP12-rapamycin complex-associated protein 1;FK506 binding protein 12-rapamycin associated protein 1;FK506 binding protein 12-rapamycin associated protein 2;FK506-binding protein 12-rapamycin complex-associated protein 1
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Involved Pathway
FRAP1 involved in several pathways and played different roles in them. We selected most pathways FRAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FRAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
FRAP1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FRAP1 itself. We selected most functions FRAP1 had, and list some proteins which have the same functions with FRAP1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
FRAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FRAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FRAP1.
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