FMNL1
-
Official Full Name
formin-like 1 -
Overview
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. -
Synonyms
FMNL1;formin-like 1;C17orf1B, FMNL, formin like;formin-like protein 1;C17orf1;8030453N10Rik;AI553564;C17orf1B;CLL associated antigen KW 13;FHOD4;FMNL;Fnrl;Formin like 1;Formin like;Formin related protein;Frls;KW 13;KW13;Leukocyte formin;MGC133052;MGC1894;MGC21878;CLL-associated antigen KW-13;KW-13
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Flag
- DDK
- Myc
- GST
- Avi
- Fc
Involved Pathway
FMNL1 involved in several pathways and played different roles in them. We selected most pathways FMNL1 participated on our site, such as RHO GTPase Effectors,RHO GTPases Activate Formins,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with FMNL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | IFT88,NPFF,ARHGEF1A,ARHGAP31,CCBP2,ARHGAP29,EMR4,RAB6A,PROK2,OPN1LW1 |
| RHO GTPases Activate Formins | AHCTF1,MKL1,MKL1B,EVL,RCC2,MIS12,NDEL1B,SKA1,FMNL2,SGOL2 |
| Signaling by Rho GTPases | NOXO1A,ARHGAP9,KTN1,ARHGAP26,PLEKHG2,FGD4,ARHGAP18,ARAP2,DEPDC1B,ARHGAP17 |
| RHO GTPase Effectors | ABI2,MKL1,RHOC,DIAPH1,NOXA1,PRC1,ERCC6L,DSN1,RHPN2,EVL |
Protein Function
FMNL1 has several biochemical functions, for example, GTPase activating protein binding,Rac GTPase binding,actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FMNL1 itself. We selected most functions FMNL1 had, and list some proteins which have the same functions with FMNL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | HAUS2,CLPTM1L,PODNL1,KLHL4,SLC25A30,PXT1,TTLL13,SFT2D2,CSN3,FAM167AA |
| GTPase activating protein binding | GNAI3,PTBP3,TUBB,MEX3B,GAPVD1,PIN1,TSC1,PLCD1,GNAO1,CDH1 |
| protein binding | RARG,SCAF8,ANXA9,CFI,RTF1,RNF220,PAF1,THEMIS2,ITPRIPL1,CA1 |
| actin filament binding | ACTN2,SPTA1,ANXA8,PKNOX2,ADD2,MYH9A,AIF1L,DBNLB,ACTN1,GAS2L2 |
| profilin binding | WIPF1,HTT,RHOQ,VASP,DIAPH1,CTTN,DIAP1,CYFIP1,EVL,PCLO |
| Rac GTPase binding | OCRL,SOD1,NOXA1,PAK2A,NCF2,ARFIP2,SRGAP1,CDKL5,PAK6,NOX1 |
Interacting Protein
FMNL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FMNL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FMNL1.
SRGAP2;GAS7;PRPF40A;XRCC6;polg_hcvj1;STRN3
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