FBXW12
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Official Full Name
F-box and WD repeat domain containing 12 -
Overview
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)). -
Synonyms
FBXW12;F-box and WD repeat domain containing 12;F box and WD 40 domain protein 12 , F box only protein 35 , FBXO35;F-box/WD repeat-containing protein 12;Fbw12;F box and WD 40 domain containing protein 12;F box and WD 40 domain protein 12;F box and WD repeat domain containing 12;F box and WD40 repeat containing protein;F box only protein 35;F box/WD repeat containing protein 12;F-box and WD-40 domain-containing protein 12;F-box only protein 35;FBW12_HUMAN;FBX12;FBXO12;FBXO35;FBXW 12;MGC120385;MGC120386;MGC120387;F-box and WD-40 domain protein 12;F-box- and WD40-repeat-containing protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FBXW12-3968H | Recombinant Human FBXW12 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FBXW12-609HCL | Recombinant Human FBXW12 cell lysate | Human | Non |
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| FBXW12-4701HF | Recombinant Full Length Human FBXW12 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 445 amino acids |
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Involved Pathway
FBXW12 involved in several pathways and played different roles in them. We selected most pathways FBXW12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXW12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FBXW12 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FBXW12 itself. We selected most functions FBXW12 had, and list some proteins which have the same functions with FBXW12. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
FBXW12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXW12 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXW12.
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