FBXO6
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Official Full Name
F-box protein 6 -
Overview
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. -
Synonyms
FBXO6;F-box protein 6;F box only protein 6;F-box only protein 6;FBG2;FBS2;FBX6;Fbx6b;F-box protein FBG2;F-box protein Fbx6;F-box/G-domain protein 2;F-box protein that recognizes sugar chains 2
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
FBXO6 involved in several pathways and played different roles in them. We selected most pathways FBXO6 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | HSPA1A,RPN1,PDIA3,SAR1B,TUSC3,UBE2D2,PARK2,CRYAB,SSR2,EIF2AK2 |
Protein Function
FBXO6 has several biochemical functions, for example, carbohydrate binding,glycoprotein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO6 itself. We selected most functions FBXO6 had, and list some proteins which have the same functions with FBXO6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | FREM1,SFTPD,GALNT6,ITLN1,LGALS2B,ACAN,LGALSLA,POC1BL,KLRK1,CLEC12A |
| glycoprotein binding | RAB14,VLDLR,THBS1,CSNK1D,EDEM2,SELP,PIP,F7,ITGAM,Shh |
| protein binding | FIBPB,PMS2,FMO4,TECPR2,SCHIP1,COASY,ZNF136,NUDCD3,C9orf116,CCL4 |
| ubiquitin protein ligase activity | RNF4,RBBP6,UBE2A,C18orf25,MSL2B,MED1,RNF24,FANCF,SIAH2L,NEDD4 |
Interacting Protein
FBXO6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO6.
HSP90AB1;CUL1;ORC4;env
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