FANCC
-
Official Full Name
Fanconi anemia, complementation group C -
Overview
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. -
Synonyms
FANCC;Fanconi anemia, complementation group C;FACC;Fanconi anemia group C protein;FA3;FAC;FLJ14675
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FANCC-12737H | Recombinant Human FANCC, GST-tagged | E.coli | Human | GST | 206-558a.a. | |
| FANCC-1724C | Recombinant Chicken FANCC | Mammalian Cells | Chicken | His |
|
|
| FANCC-3813Z | Recombinant Zebrafish FANCC | Mammalian Cells | Zebrafish | His |
|
|
| FANCC-3828H | Recombinant Human FANCC Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| FANCC-6333HCL | Recombinant Human FANCC 293 Cell Lysate | HEK293 | Human | Non |
|
|
| FANCC-4664HF | Recombinant Full Length Human FANCC Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 558 amino acids |
|
| FANCC-497H | Recombinant Human FANCC Protein (1-558 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 1-558 aa |
|
Involved Pathway
FANCC involved in several pathways and played different roles in them. We selected most pathways FANCC participated on our site, such as Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FANCC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fanconi Anemia Pathway | ATRIP,RMI2,USP36,MLH1,APITD1,STRA13,TOP3B,FANCF,PALB2,FANCM |
Protein Function
FANCC has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FANCC itself. We selected most functions FANCC had, and list some proteins which have the same functions with FANCC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RTF1,IFIT1,RBFOX2,MCPH1,LTBR,CLOCKA,CALB1,SGCG,CASQ2,CCNL2 |
Interacting Protein
FANCC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FANCC here. Most of them are supplied by our site. Hope this information will be useful for your research of FANCC.
FANCE;SPTAN1;HSP90B1;FANCA;CDK1;HSP90AB1;q96be0_human;FANCG;BUB1;EGFR;NRAS
Resources
Related Services
Related Products
References
- Mi, J; Qiao, F; et al. FANCG is phosphorylated at serines 383 and 387 during mitosis. MOLECULAR AND CELLULAR BIOLOGY 24:8576-8585(2004).
- Donahue, SL; Lundberg, R; et al. Deficient regulation of DNA double-strand break repair in Fanconi anemia fibroblasts. JOURNAL OF BIOLOGICAL CHEMISTRY 278:29487-29495(2003).
