FAM126A
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Official Full Name
family with sequence similarity 126, member A -
Overview
The protein encoded by this gene may play a part in the beta-catenin/Lef signaling pathway. Expression of this gene is down-regulated by beta-catenin. Defects in this gene are a cause of hypomyelination with congenital cataract (HCC). -
Synonyms
FAM126A;family with sequence similarity 126, member A;hyccin;down regulated by Ctnnb1;a;DRCTNNB1A;HCC;HYCC1;Down regulated by Ctnnb1 a;Down regulated by CTNNB1 protein A;Down-regulated by CTNNB1 protein A;Family with sequence similarity 126 member A;HLD5;HYCCI_HUMAN;Protein FAM126A;down regulated by Ctnnb1, a
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Chicken
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FAM126A-11665Z | Recombinant Zebrafish FAM126A | Mammalian Cell | Zebrafish | His |
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| FAM126A-1563R | Recombinant Rhesus monkey FAM126A Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| FAM126A-2667C | Recombinant Chicken FAM126A | Mammalian Cell | Chicken | His |
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| FAM126A-3695H | Recombinant Human FAM126A Protein, GST-tagged | Wheat Germ | Human | GST |
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| FAM126A-5485M | Recombinant Mouse FAM126A Protein | Mammalian Cell | Mouse | His |
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| FAM126A-6436HCL | Recombinant Human FAM126A 293 Cell Lysate | HEK293 | Human | Non |
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| FAM126A-1388R | Recombinant Rhesus Macaque FAM126A Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| FAM126A-1388R-B | Recombinant Rhesus Macaque FAM126A Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| FAM126A-2978M | Recombinant Mouse FAM126A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FAM126A-2978M-B | Recombinant Mouse FAM126A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FAM126A-4521HF | Recombinant Full Length Human FAM126A Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 521 amino acids |
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Involved Pathway
FAM126A involved in several pathways and played different roles in them. We selected most pathways FAM126A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FAM126A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FAM126A has several biochemical functions, for example, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM126A itself. We selected most functions FAM126A had, and list some proteins which have the same functions with FAM126A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| signal transducer activity | PTGER1B,CCR9A,GRM2A,PRKCE,RGS9,TRIM13,TAAR2,PTK2,OLFR147,TAS2R114 |
Interacting Protein
FAM126A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM126A here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM126A.
Resources
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References
- Miyamoto, Y; Torii, T; et al. Hypomyelinating leukodystrophy-associated missense mutant of FAM126A/hyccin/DRCTNNB1A aggregates in the endoplasmic reticulum. JOURNAL OF CLINICAL NEUROSCIENCE 21:1033-1039(2014).
- Wallner, S; Grandl, M; et al. Monocyte to Macrophage Differentiation Goes along with Modulation of the Plasmalogen Pattern through Transcriptional Regulation. PLOS ONE 9:-(2014).
