FAAH2
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Official Full Name
fatty acid amide hydrolase 2 -
Overview
This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate. -
Synonyms
FAAH2;fatty acid amide hydrolase 2;AMDD, amidase domain containing;fatty-acid amide hydrolase 2;FAAH 2;FLJ31204;RP11 479E16.1;oleamide hydrolase 2;amidase domain containing;anandamide amidohydrolase 2;amidase domain-containing protein;AMDD
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FAAH2-2459H | Recombinant human FAAH2, His-tagged | E.coli | Human | His | ||
| FAAH2-3628H | Recombinant Human FAAH2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FAAH2-6480HCL | Recombinant Human FAAH2 293 Cell Lysate | HEK293 | Human | Non |
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| FAAH2-4419HF | Recombinant Full Length Human FAAH2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 532 amino acids |
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| FAAH2-849H | Recombinant Human FAAH2 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | Human | His | Full L. 1-532aa |
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| RFL29064HF | Recombinant Full Length Human Fatty-Acid Amide Hydrolase 2(Faah2) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-532aa) |
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Involved Pathway
FAAH2 involved in several pathways and played different roles in them. We selected most pathways FAAH2 participated on our site, such as Arachidonic acid metabolism,Metabolism,Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAAH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of lipids and lipoproteins | PTGDSA,DECR1,PTGR1,ACOT9.1,CYP46A1,TPTE,ACOT9,MED15,COL4A3BP,APOF |
| Metabolism | SULT1ST5,CIAO1,CYP2B6,CKB,CYP2K18,GYG1A,PDK2,YAP1,ZDHHC21,ATP5L |
| Arachidonic acid metabolism | CYP1A1,CYP2B6,AKR1C3,PLA2G12B,GPX5,CYP2C45,CYP2C54,GPX3,CYP2C70,GGT5 |
Protein Function
FAAH2 has several biochemical functions, for example, carbon-nitrogen ligase activity, with glutamine as amido-N-donor,hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FAAH2 itself. We selected most functions FAAH2 had, and list some proteins which have the same functions with FAAH2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbon-nitrogen ligase activity, with glutamine as amido-N-donor | GATB,FAAH2B,FAAH,PET112L,FAAH2A |
| hydrolase activity | TDRD9,TRY,PSMB11,CES1D,MBLAC1,MTMR7A,ST14A,RNASEL4,PLA2G2F,TMPRSS13B |
Interacting Protein
FAAH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAAH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAAH2.
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References
- Durinck, S; Stawiski, EW; et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma. NATURE GENETICS 47:13-+(2015).
- Bennetzen, MF; Wellner, N; et al. Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss. INTERNATIONAL JOURNAL OF OBESITY 35:1377-1384(2011).
