EXOC2
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Official Full Name
exocyst complex component 2 -
Overview
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. -
Synonyms
EXOC2;exocyst complex component 2;SEC5 like 1 (S. cerevisiae) , SEC5L1;FLJ11026;Sec5p;SEC5-like 1;exocyst complex component Sec5;SEC5;SEC5L1
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Chicken
- Rat
- Mammalian Cell
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EXOC2-10882Z | Recombinant Zebrafish EXOC2 | Mammalian Cell | Zebrafish | His |
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| EXOC2-1516R | Recombinant Rhesus monkey EXOC2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| EXOC2-1519C | Recombinant Chicken EXOC2 | Mammalian Cell | Chicken | His |
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| EXOC2-2165R | Recombinant Rat EXOC2 Protein | Mammalian Cell | Rat | His |
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| EXOC2-1341R | Recombinant Rhesus Macaque EXOC2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| EXOC2-1341R-B | Recombinant Rhesus Macaque EXOC2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| EXOC2-1822R | Recombinant Rat EXOC2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| EXOC2-1822R-B | Recombinant Rat EXOC2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
EXOC2 involved in several pathways and played different roles in them. We selected most pathways EXOC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
EXOC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by EXOC2 itself. We selected most functions EXOC2 had, and list some proteins which have the same functions with EXOC2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
EXOC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOC2.
Resources
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References
- Evers, C; Maas, B; et al. Mosaic Deletion of EXOC6B: Further Evidence for An Important Role of the Exocyst Complex in the Pathogenesis of Intellectual Disability. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:3088-3094(2014).
- Liu, DM; Novick, P; et al. Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p. JOURNAL OF CELL BIOLOGY 207:59-72(2014).
