EVI5
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Official Full Name
ecotropic viral integration site 5 -
Overview
EVI5 is a novel centrosomal protein with a complex expression pattern and subcellular localization, possibly involved in centrosome stability and dynamics. It may act as an oncogene. -
Synonyms
EVI5;ecotropic viral integration site 5;NB4S;ecotropic viral integration site 5 protein homolog;EVI-5;neuroblastoma stage 4S gene protein;dJ846D11.1 (ecotropic viral integration site 5)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EVI5-12580H | Recombinant Human EVI5, GST-tagged | E.coli | Human | GST | 700-810a.a. |
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| EVI5-3548H | Recombinant Human EVI5 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EVI5-6517HCL | Recombinant Human EVI5 293 Cell Lysate | HEK293 | Human | Non |
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| EVI5-4377HF | Recombinant Full Length Human EVI5 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 810 amino acids |
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Involved Pathway
EVI5 involved in several pathways and played different roles in them. We selected most pathways EVI5 participated on our site, such as Aurora B signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EVI5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aurora B signaling | RACGAP1,CDCA8,CENPA,KIF2C,PEBP1,SEPT1,SGOL1,AURKB,CBX5,TACC1 |
Protein Function
EVI5 has several biochemical functions, for example, GTPase activator activity,Rab GTPase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EVI5 itself. We selected most functions EVI5 had, and list some proteins which have the same functions with EVI5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KLK15,CEBPB,TPM1,CCDC22,VEGFB,RMND1,SGTB,FZD8,WDYHV1,OSBPL6 |
| Rab GTPase binding | ALS2,HACE1,RAB3GAP2,RAB11FIP1,EVI5L,RAB11FIP3,LLGL2,GAS8,ANXA2,BICD1 |
| GTPase activator activity | RGS5,RABEP2,ELMOD1,WNT11,STXBP5L,SRGAP1,RGS11,RASAL2,GRTP1,TBC1D7 |
Interacting Protein
EVI5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EVI5 here. Most of them are supplied by our site. Hope this information will be useful for your research of EVI5.
PLK1;FBXO5;o68749_yerpe;pyc;Cenpe;RAB11A;Rab11a;Rbm8a;CHMP4B;RNF41
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References
- Wyrebska, A; Pawlowska, Z; et al. Proteomic Analysis of Proteins Engaged in alpha-Methylene-delta-Lactone Cytotoxic Effects in Hormone-Independent Breast Cancer MDA-MB-231 Cells. CHEMICAL BIOLOGY & DRUG DESIGN 84:300-306(2014).
- Rao, N; Song, FY; et al. Proteomic analysis of fibroblastema formation in regenerating hind limbs of Xenopus laevis froglets and comparison to axolotl. BMC DEVELOPMENTAL BIOLOGY 14:-(2014).
