ERLEC1
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Official Full Name
endoplasmic reticulum lectin 1 -
Overview
This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21. -
Synonyms
ERLEC1;endoplasmic reticulum lectin 1;C2orf30, chromosome 2 open reading frame 30;CL25084;ERLECTIN;erlectin 1;XTP3 B;XTP3TPB;C2orf30;CL24936;CL2508;ER lectin;RP23 20N14.5;XTP3 transactivated gene B protein;XTP3 transactivated protein B;XTP3B;XTP3-transactivated protein B;XTP3-transactivated gene B protein;cancer invasion and metastasis-related;CIM;XTP3-B
Recombinant Proteins
- Rhesus macaque
- Mouse
- Zebrafish
- Human
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ERLEC1-1493R | Recombinant Rhesus monkey ERLEC1 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| ERLEC1-5304M | Recombinant Mouse ERLEC1 Protein | Mammalian Cells | Mouse | His |
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| ERLEC1-9918Z | Recombinant Zebrafish ERLEC1 | Mammalian Cells | Zebrafish | His |
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| ERLEC1-6552HCL | Recombinant Human ERLEC1 293 Cell Lysate | HEK293 | Human | Non |
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| ERLEC1-1318R | Recombinant Rhesus Macaque ERLEC1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ERLEC1-1318R-B | Recombinant Rhesus Macaque ERLEC1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ERLEC1-1463H | Recombinant Human ERLEC1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| ERLEC1-2852M | Recombinant Mouse ERLEC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ERLEC1-2852M-B | Recombinant Mouse ERLEC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Erlec1-2861M | Recombinant Mouse Erlec1 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
ERLEC1 involved in several pathways and played different roles in them. We selected most pathways ERLEC1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERLEC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | HSP70,UBE2D1A,BAX,PDIA6,DNAJA2,HSPA1A,SEC31B,MAPK10,NPLOC4,RPN2 |
Protein Function
ERLEC1 has several biochemical functions, for example, glycoprotein binding,protein binding,unfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERLEC1 itself. We selected most functions ERLEC1 had, and list some proteins which have the same functions with ERLEC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ADAMTS3,NAALADL2,DDR2,BAZ1B,HES1,JPH2,SPAG9,HSPE1,ZC3H12A,PLOD3 |
| glycoprotein binding | ITGB2,Itgam&Itgb2,Serpina1b,LGALS1,FBXO2,TGFB1,VIM,STX1A,RAB14,FBXO6 |
| unfolded protein binding | CCT3,CALR3B,UGGT1,CCDC102A,CDC37,DNAJB4,HSP26,CCT4,PPIB,DNAJB11 |
Interacting Protein
ERLEC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERLEC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERLEC1.
env;env;GH1;TNFRSF1A;STK11;Ncstn;Sel1l
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References
- Dizaji, NB; Basseri, HR; et al. Molecular characterization of calreticulin from Anopheles stephensi midgut cells and functional assay of the recombinant calreticulin with Plasmodium berghei ookinetes. GENE 550:245-252(2014).
- Hong, D; Bai, YP; et al. Ox-LDL induces endothelial cell apoptosis via the LOX-1-dependent endoplasmic reticulum stress pathway. ATHEROSCLEROSIS 235:310-317(2014).
