ERF
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Official Full Name
Ets2 repressor factor -
Overview
Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They;share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al.,;1997 (PubMed 9192842)). For further information on ETS transcription factors, see ETS1 (MIM 164720). -
Synonyms
ERF;Ets2 repressor factor;ETS domain-containing transcription factor ERF;PE 2;PE2;PE-2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ERF-2676H | Recombinant Human ERF protein, His-tagged | E.coli | Human | His | 138-323 aa | |
| ERF-3467H | Recombinant Human ERF Protein, GST-tagged | Wheat Germ | Human | GST |
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| ERF-4028Z | Recombinant Zebrafish ERF | Mammalian Cells | Zebrafish | His |
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| ERF-5294M | Recombinant Mouse ERF Protein | Mammalian Cells | Mouse | His |
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| ERF-6561HCL | Recombinant Human ERF 293 Cell Lysate | HEK293 | Human | Non |
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| ERF-2846M | Recombinant Mouse ERF Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ERF-2846M-B | Recombinant Mouse ERF Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ERF-4565HF | Recombinant Full Length Human ERF Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 548 amino acids |
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Involved Pathway
ERF involved in several pathways and played different roles in them. We selected most pathways ERF participated on our site, such as Cellular Senescence,Cellular responses to stress,Oncogene Induced Senescence, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cellular Senescence | TERF1,KDM6B,UBN1,KAT5,HIST2H3C,RBB4L,CDK4,PHC3,ACD,HIST1H1E |
| Cellular responses to stress | DPF1,PHC1,CBX8A,MAPKAPK2B,WIPI1,AGO1,C11orf73,HIST4H4,HIST2H3C,DYNLL2A |
Protein Function
ERF has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding,sequence-specific DNA binding,transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ERF itself. We selected most functions ERF had, and list some proteins which have the same functions with ERF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | FOXQ2,MNX2A,HOXD13A,PRRX2,IRX3B,IKZF1,GLI2A,ZSCAN16,NR2F6B,HIC1 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | FLI1,RUNX3,ZMYM5,ELF2,FOXB1A,ATF5A,SIM1B,PLAGL1,EPAS1B,LMO2 |
| transcription corepressor activity | TBL1X,LHX1,BHLHE40,MECP2,DNMT3B,E4F1,ZMYND11,DR1,HEYL,BRD7 |
Interacting Protein
ERF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERF here. Most of them are supplied by our site. Hope this information will be useful for your research of ERF.
CSNK1A1;SEC16A;XRCC5;Oxnad1;SGTB
Resources
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References
- Wang, L; Stebbings, R; et al. Quantification of Cells with Specific Phenotypes II: Determination of CD4 Expression Level on Reconstituted Lyophilized Human PBMC Labelled with Anti-CD4 FITC Antibody. CYTOMETRY PART A 87A:254-261(2015).
- Bai, H; Lan, JP; et al. Identification and expression analysis of components involved in rice Xa21-mediated disease resistance signalling. PLANT BIOLOGY 14:914-922(2012).
