ENC1
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Official Full Name
ectodermal-neural cortex 1 (with BTB-like domain) -
Overview
DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. Polyak et al. (1997) -
Synonyms
ENC1;ectodermal-neural cortex 1 (with BTB-like domain);NRPB;ectoderm-neural cortex protein 1;ENC 1;kelch like 37 (Drosophila);KLHL37;PIG10;TP53I10;CCL 28;CCL28;Ectoderm neural cortex protein 1;Ectodermal neural cortex (with BTB like domain);ENC-1;ENC1_HUMAN;FLJ39259;Kelch like 35;Kelch-like protein 37;KLHL 35;KLHL35;Nuclear matrix protein NRP/B;Nuclear restricted protein BTB domain like (brain);p53 induced gene 10 protein;p53-induced gene 10 protein;PIG 10;Tumor protein p53 inducible protein 10;kelch-like 35;kelch-like 37;OTTHUMP00000128235;OTTHUMP00000222054;ectodermal-neural cortex (with BTB-lik
Recombinant Proteins
- Rhesus macaque
- Zebrafish
- Human
- Mouse
- Mammalian Cells
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
ENC1 involved in several pathways and played different roles in them. We selected most pathways ENC1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ENC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ENC1 has several biochemical functions, for example, actin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ENC1 itself. We selected most functions ENC1 had, and list some proteins which have the same functions with ENC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NSMAF,CASP1,ZFPM2,SMU1,CEP63,MIEN1,NDUFS3,VIPAS39,TMEM194,MRPL41 |
| actin binding | KLHL33,TPM4,KCNMA1,ACE,CAPZA1B,KLHL3,MICAL1,PARVB,SNTA1,VASPA |
Interacting Protein
ENC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENC1.
HSP90AB1
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References
- Feng, J; Hong, LC; et al. Identification of a subtype-specific ENC1 gene related to invasiveness in human pituitary null cell adenoma and oncocytomas. JOURNAL OF NEURO-ONCOLOGY 119:307-315(2014).
- Mabuchi, K; Fraser, TH; et al. Revision of the systematics of the cardinalfishes (Percomorpha: Apogonidae) based on molecular analyses and comparative reevaluation of morphological characters. ZOOTAXA 3846:151-203(2014).
