EIF4G3
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Official Full Name
eukaryotic translation initiation factor 4 gamma, 3 -
Overview
Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1. -
Synonyms
EIF4G3;eukaryotic translation initiation factor 4 gamma, 3;eIF4G 3;eIF4GII;eIF-4G 3;eukaryotic translation initiation factor 4 gamma 3;eIF-4-gamma 3;eIF-4-gamma II
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EIF4G3-3212H | Recombinant Human EIF4G3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EIF4G3-6645HCL | Recombinant Human EIF4G3 293 Cell Lysate | HEK293 | Human | Non |
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| EIF4G3-4298HF | Recombinant Full Length Human EIF4G3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 515 amino acids |
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Involved Pathway
EIF4G3 involved in several pathways and played different roles in them. We selected most pathways EIF4G3 participated on our site, such as RNA transport,Viral myocarditis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4G3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Viral myocarditis | MYH7,SGCG,HLA-C,PRF1,CAV1,SGCD,CD40LG,HLA-DQA2,ACTB,HLA-DQA1 |
| RNA transport | EEF1A1L1,RANGAP1A,THOC5,NUP62,EIF4A1B,CLNS1A,SIP1,THOC7,TACC3,PABPC1L2A |
Protein Function
EIF4G3 has several biochemical functions, for example, RNA cap binding,poly(A) RNA binding,translation factor activity, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4G3 itself. We selected most functions EIF4G3 had, and list some proteins which have the same functions with EIF4G3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation initiation factor activity | EIF3E,EIF2D,EIF1B,EIF4H,EIF2S1B,EIF3S6IP,EIF4G1,EIF4A1B,DHX29,EIF3EA |
| translation factor activity, RNA binding | CPEB1A,ABCF1,CPEB4,SOX11,EEF2K,PPP1R2P9,CPEB1,EIF4H,EIF4E2,EIF4A1 |
| RNA cap binding | EIF4E2,LARP1,NCBP1,NCBP2,EIF4A1,EIF4E,SNUPN |
| poly(A) RNA binding | XRN2,HNRNPA1,PEG10,HEATR6,CDKN2A,UBE2N,KCTD12,MRPS11,FXR1,RPS25 |
Interacting Protein
EIF4G3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4G3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4G3.
PABPC1;saicar;PKM;EIF3H;EIF4A1;NCBP1;EIF4A2;USP10;HSPB1;VAV2;q81kg1_bacan;yqeH;csgG;terD;MKNK1;15-deoxy-delta(12,14;ere_dna
EIF4G3 Related Signal Pathway
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References
- Jensik, PJ; Vargas, JD; et al. DEAF1 Binds Unmethylated and Variably Spaced CpG Dinucleotide Motifs. PLoS One 9:-(2014).
- Hashimoto, R; Ikeda, M; et al. Common variants at 1p36 are associated with superior frontal gyrus volume. TRANSLATIONAL PSYCHIATRY 4:-(2014).
