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EIF3H

Official Full Name

eukaryotic translation initiation factor 3, subunit H
Overview

The elF3H (eIF3-p40) is a subunit of eukaryotic translation initiation factor 3 (eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to 170 kd. elF3-p40 is constitutively
Synonyms

EIF3H; eukaryotic translation initiation factor 3, subunit H; EIF3S3, eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa; eukaryotic translation initiation factor 3 subunit H; eIF3 gamma; eIF3 p40; eIF-3-gamma; eIF3 p40 subunit; eu;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	EIF3H-3185H	Recombinant Human EIF3H Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	EIF3H-3063H	Recombinant Human EIF3H, His-tagged	E.coli	His	1-352	Inquiry
Human	EIF3H-6659HCL	Recombinant Human EIF3H 293 Cell Lysate	HEK293	Non		Inquiry
Human	EIF3H-4269HF	Recombinant Full Length Human EIF3H Protein, GST-tagged	In Vitro Cell Free System	GST	352 amino acids	Inquiry
Mouse	Eif3h-2780M	Recombinant Mouse Eif3h Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Rat	EIF3H-2061R	Recombinant Rat EIF3H Protein	Mammalian Cell	His		Inquiry
Rat	EIF3H-1718R	Recombinant Rat EIF3H Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rat	EIF3H-1718R-B	Recombinant Rat EIF3H Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	EIF3H-2640C	Recombinant Chicken EIF3H	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

EIF3H involved in several pathways and played different roles in them. We selected most pathways EIF3H participated on our site, such as RNA transport, Measles, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA transport	NUP133;EEF1A1L2;EIF2B4;NUP210;THOC6;THOC1;EIF2B5;NUP88;EIF3EA
Measles	PIK3R2;CCNE1;Ifna11;Il2;EIF2AK2;CCND1;AKT2;IFNA5;IL12A

EIF3H has several biochemical functions, for example, poly(A) RNA binding, protein binding, contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3H itself. We selected most functions EIF3H had, and list some proteins which have the same functions with EIF3H. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	HNRNPH3;RAN;HDLBP;HIST1H4M;ZFC3H1;TES;DKC1;SKIV2L2;ERI3
protein binding	PACSIN1;STARD13;L3MBTL3;DNM3;RAD51;HMOX1;SCAMP5;HNRPDL;PUM1
contributes_to translation initiation factor activity	EIF3A;EIF3C;EIF3L;EIF3BA;EIF3EA;EIF3HA;EIF2B2;EIF3D;EIF3F

EIF3H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3H here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3H.

DISC1; ABI3; EIF3A; EIF4A2; Eif3a; EIF3B; ORF

Research Area

Gao, F; Kasprzak, WK; et al. The 3 ' Untranslated Region of Pea Enation Mosaic Virus Contains Two T-Shaped, Ribosome-Binding, Cap-Independent Translation Enhancers. JOURNAL OF VIROLOGY 88:11696-11712(2014).

Roobol, A; Roobol, J; et al. The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h. BIOCHEMICAL JOURNAL 458:213-224(2014).