EIF2D
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Official Full Name
eukaryotic translation initiation factor 2D -
Overview
This gene encodes a translation initiation factor involved in the recruitment and delivery of aminoacyl-tRNAs to the P-site of the eukaryotic ribosome in a GTP-independent manner. This gene was previously referred to as ligatin, but is now known to localize to the cytoplasm and localize and function with translation factors. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
EIF2D;eukaryotic translation initiation factor 2D;LGTN;HCA56;Hepatocellular carcinoma associated antigen 56;Hepatocellular carcinoma-associated antigen 56;LIGA_HUMAN;Ligatin;OTTHUMP00000034537;OTTHUMP00000034538
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Chicken
- Rat
- Human
- Mouse
- Mammalian Cells
- Wheat Germ
- HEK293
- E.coli
- In Vitro Cell Free System
- His
- Non
- GST
- Myc&DDK
- His&T7
- His&Fc&Avi
Involved Pathway
EIF2D involved in several pathways and played different roles in them. We selected most pathways EIF2D participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
EIF2D has several biochemical functions, for example, receptor activity,translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2D itself. We selected most functions EIF2D had, and list some proteins which have the same functions with EIF2D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation initiation factor activity | EIF3BA,DENR,EIF4EB,MCTS1,EIF4G1,EIF4A1,BRF1A,EIF5,EIF2S3Y,EIF3S6IP |
| receptor activity | SLC20A2,IL10RB,MED30,MED16,CADM3,UBXN6,GRIA2B,SV2A,RTN4RL1,OGFRL1 |
Interacting Protein
EIF2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2D here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2D.
RAD51;pi3p;CDC5L
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References
