DTNB
-
Official Full Name
dystrobrevin, beta -
Overview
This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
DTNB;dystrobrevin, beta;dystrobrevin beta;Beta dystrobrevin;Beta-dystrobrevin;DTN B;DTN-B;DTNB_HUMAN
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
DTNB involved in several pathways and played different roles in them. We selected most pathways DTNB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DTNB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DTNB has several biochemical functions, for example, protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTNB itself. We selected most functions DTNB had, and list some proteins which have the same functions with DTNB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | COASY,MAPRE1,INPP5K,TP53INP1,MARK3,LTBP2,MKRN2,SAMHD1,MTRR,COPS7A |
| zinc ion binding | TCF19,LMO1,PHF20B,TAF15,ZFAND4,PPARG,CNOT4B,TRAIP,ADH1,ADAM22 |
Interacting Protein
DTNB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTNB here. Most of them are supplied by our site. Hope this information will be useful for your research of DTNB.
DMD;NUP62;TRAF2;CEP63;HMG20A
Resources
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References
- Mnif, IH; Siala, R; et al. A Cysteine Protease Isolated from the Latex of Ficus microcarpa: Purification and Biochemical Characterization. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 175:1732-1744(2015).
- Plancarte, A; Nava, G; et al. Purification and kinetic analysis of cytosolic and mitochondrial thioredoxin glutathione reductase extracted from Taenia solium cysticerci. EXPERIMENTAL PARASITOLOGY 149:65-73(2015).
