DPY30
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Official Full Name
dpy-30 homolog -
Overview
DPY30 is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 (PubMed;17500065)). -
Synonyms
DPY30;dpy-30 homolog (C. elegans);protein dpy-30 homolog;HDPY 30;Saf19;dpy-30L;dpy-30-like protein;HDPY-30
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DPY30 involved in several pathways and played different roles in them. We selected most pathways DPY30 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,PKMTs methylate histone lysines, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPY30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin modifying enzymes | SMYD3,KDM2B,SUZ12B,ENY2,EHMT2,KDM3A,PADI6,SMARCA4,MBD3,KANSL2 |
| PKMTs methylate histone lysines | RBBP5,SMYD3,SUZ12A,EED,ATF7IP,ASH2L,SUZ12B,PRDM16,SMYD2,SUZ12 |
| Chromatin organization | AEBP2,MEAF6,KDM5BB,PRMT7,PRMT5,MORF4L2,GATAD2A,MSL2A,SAP30,KDM3B |
Protein Function
DPY30 has several biochemical functions, for example, contributes_to histone methyltransferase activity (H3-K4 specific),identical protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPY30 itself. We selected most functions DPY30 had, and list some proteins which have the same functions with DPY30. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | MNS1,SIAH1A,CLDN16,PNMA5,PRPF3,NISCH,KHDC1B,LECT2,TRIP10,UGP2 |
| protein homodimerization activity | IL6R,VIL1,CTBP2A,RAB11FIP2,ENO3,MIXL1,TERFA,CCDC88A,S100A1,TRIM8 |
| protein binding | E2F8,MNDA,SYN1,EXOSC5,RBM42,TMEM171,ASCL1,PTGDS,RAP1A,HSPBP1 |
| contributes_to histone methyltransferase activity (H3-K4 specific) | DYDC2,ASH2L,RBBP5,DYDC1,CXXC1 |
Interacting Protein
DPY30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPY30 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPY30.
ASH2L;PSMD14;TMCC2;CXXC1
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References
- Dheilly, NM; Lelong, C; et al. Gametogenesis in the Pacific Oyster Crassostrea gigas: A Microarrays-Based Analysis Identifies Sex and Stage Specific Genes. PLOS ONE 7:-(2012).
- Petty, E; Laughlin, E; et al. Regulation of DCC Localization by HTZ-1/H2A. Z and DPY-30 Does not Correlate with H3K4 Methylation Levels. PLOS ONE 6:-(2011).
