DPEP1
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Official Full Name
dipeptidase 1 (renal) -
Synonyms
DPEP1;dipeptidase 1 (renal);3002;ENSG00000015413;MDP;RDP;MBD1;16q24.3;dipeptidase 1;dipeptidase 1;hRDP;renal dipeptidase;dehydropeptidase-I;microsomal dipeptidase;EC 3.4.13.19
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- Sheep
- HEK293
- Mammalian Cells
- E.coli
- Human Cells
- Yeast
- His
- Fc
- Non
- Avi
Involved Pathway
DPEP1 involved in several pathways and played different roles in them. We selected most pathways DPEP1 participated on our site, such as Aflatoxin activation and detoxification,Arachidonic acid metabolism,Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPEP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biological oxidations | CYP4T8,CYP24A1,GSTK1,BPNT1,TPMT.2,CYP2K18,GLYAT,ADH8B,CYP2W1,GLYATL1 |
| Aflatoxin activation and detoxification | CYP3C1,ACY3.1,CYP1A2,DPEP2,ACY3.2,CYP3A4,FAM84B,GGTLC1,PRKRA,CYP3A5 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | PTGR1,DPEP2,ALOX5B.3,ALOX5B.2,ALOX5AP |
| Eicosanoid Synthesis | PNPLA8,ALOX5AP |
| Metabolism | CES1,C20orf7,GLTPD1,ST3GAL3A,SLC35B3,B3GNT2A,CYP4F12,CEPT1A,MED25,TPH2 |
| Metabolism of lipids and lipoproteins | MED10,APOBB.1,GDF1,TPTE,OSBP,MED21,MED7,G0S2,ACOT11A,GLTPA |
| leukotriene biosynthesis | DPEP2 |
| Arachidonic acid metabolism | CYP4F14,ALOX5A,PLA2G12B,CYP4A12A,PLA2G4B,ALOX12B,PTGIS,GGTLC1,PLA2G4AA,GGT5A |
Protein Function
DPEP1 has several biochemical functions, for example, GPI anchor binding,cysteine-type endopeptidase inhibitor activity involved in apoptotic process,dipeptidyl-peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DPEP1 itself. We selected most functions DPEP1 had, and list some proteins which have the same functions with DPEP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase inhibitor activity involved in apoptotic process | LEF1,PRDX5,NOL3,CD27,NAIP1,MT3,BIRC5,TNFSF14,C1QL4L,IGF1RB |
| dipeptidyl-peptidase activity | DPEP2,DPP3,DPP4,NAALAD2,FAP,DPP7,DPEP3,PRCP,DPP8 |
| metalloexopeptidase activity | METAP2B,ERAP1,METAP1,NUDT16,RNPEP,DPEP2,METAP2A,DPEP3,METAP1D,METAP2 |
| protein binding | PYGB,PSMD9,PICALM,RND2,DLL1,TP53INP1,SOCS3,CDK7,RFX5,CDC23 |
| zinc ion binding | IDE,SOLH,ADAM21,KLF7,ABP1,ZZZ3,BIRC2,QPCTLA,RNF185,FHL2 |
| modified amino acid binding | MUT,CBS,MTHFR,CPS1,NOX4 |
| GPI anchor binding | NIPAL1,MPPE1,CEACAM5,THY1,VNN1 |
| metallodipeptidase activity | PGCP |
Interacting Protein
DPEP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPEP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPEP1.
APPBP2;KIF1BP
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References
- Danielsson, A; Ponten, F; et al. The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling. PLOS ONE 9:-(2014).
- Nicastri, A; Gaspari, M; et al. N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. JOURNAL OF PROTEOME RESEARCH 13:4932-4941(2014).
