DIAPH2
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Official Full Name
diaphanous homolog 2 -
Overview
The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
DIAPH2;diaphanous homolog 2 (Drosophila);diaphanous (Drosophila, homolog) 2;protein diaphanous homolog 2;DIA;DIA2;POF;POF2;diaphorase-2;diaphanous-related formin-2;DRF2;FLJ11167
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Involved Pathway
DIAPH2 involved in several pathways and played different roles in them. We selected most pathways DIAPH2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DIAPH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
DIAPH2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DIAPH2 itself. We selected most functions DIAPH2 had, and list some proteins which have the same functions with DIAPH2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
DIAPH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DIAPH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DIAPH2.
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References
- Pan, JJ; Lordier, L; et al. The formin DIAPH1 (mDia1) regulates megakaryocyte proplatelet formation by remodeling the actin and microtubule cytoskeletons. BLOOD 124:3967-3977(2014).
- Chang, ALS; Atzmon, G; et al. Identification of Genes Promoting Skin Youthfulness by Genome-Wide Association Study. JOURNAL OF INVESTIGATIVE DERMATOLOGY 134:651-657(2014).
