DHX34

  • Official Full Name

    DEAH (Asp-Glu-Ala-His) box polypeptide 34

  • Overview

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. It is mapped to the glioma 19q tumor suppressor region and is a tumor suppressor candidate gene.

  • Synonyms

    DHX34;DEAH (Asp-Glu-Ala-His) box polypeptide 34;DDX34, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 34;probable ATP-dependent RNA helicase DHX34;KIAA0134;DEAH box protein 34;probable ATP-dependent helicase DHX34;DEAD/H (Asp-Glu-Ala-Asp/His) box po

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • His&Fc&Avi
  • Myc&DDK
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
DHX34-4577M Recombinant Mouse DHX34 Protein Mammalian Cells Mouse His
DHX34-6847Z Recombinant Zebrafish DHX34 Mammalian Cells Zebrafish His
DHX34-2366M Recombinant Mouse DHX34 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DHX34-2366M-B Recombinant Mouse DHX34 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Dhx34-2558M Recombinant Mouse Dhx34 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK
DHX34-2HFL Recombinant Human DHX34 Protein, Full Length, C-FLAG tagged HEK293 Human Flag Full L. Full Length
DHX34-5176H Recombinant Human DHX34 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK

    Involved Pathway

    DHX34 involved in several pathways and played different roles in them. We selected most pathways DHX34 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    DHX34 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX34 itself. We selected most functions DHX34 had, and list some proteins which have the same functions with DHX34. You can find most of the proteins on our site.

    Function Related Protein
    nucleotide binding NPR1A,Atp8a2,LACE1B,DNAJC17,ROCK2B,DDX39AA,UBE2QL1,SETD1BA,KIF27,MXC
    nucleic acid binding ZNF219,GRSF1,JRKL,ZSCAN4C,SCAND3,ZFML,ZFP667,ZFP74,ZNF831,HNRNPA0A
    RNA binding SAMHD1,PPIE,SNRNP70,ZFP36L3,PAIP1,KHDRBS1B,RPL24,XPO5,MPHOSPH6,RPUSD1
    helicase activity DDX19,DDX51,UPF1,HELQ,EP400,EIF4A1B,HELLS,MCM3L,CHD6,MCM8
    ATP-dependent RNA helicase activity DDX25,DDX49,EIF4A1,DDX55,TMEM38A,DDX5,DDX54,DDX42,DDX4,DDX23
    poly(A) RNA binding RIMS1,RPL17,PRPF3,SNIP1,PURA,ZNFX1,STAU1,PARP12,RPS12,H2-Q10
    ATP binding MAP3K3,DCLK2,KIF20A,MYO1E,PRPF4BA,ATP13A4,MAP4K4,SMG1,ADCY8,CKBB
    hydrolase activity MBLAC2,DDHD2,CAPN3B,CES1C,CNOT6L,PNPLA1,DPYSL2B,SPINT1A,MMP1A,PTPRFB

    Interacting Protein

    DHX34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX34 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX34.

    Resources

    References

    • Casadio, A; Longman, D; et al. Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals. EMBO REPORTS 16:71-78(2015).
    • Castillo, A; Kramer, N; et al. 19q13.32 microdeletion syndrome: Three new cases. EUROPEAN JOURNAL OF MEDICAL GENETICS 57:654-658(2014).

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