DGKB
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Official Full Name
diacylglycerol kinase, beta 90kDa -
Overview
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. -
Synonyms
DGKB;diacylglycerol kinase, beta 90kDa;DAGK2, diacylglycerol kinase, beta (90kD);diacylglycerol kinase beta;DGK;DGK BETA;KIAA0718;DAG kinase beta;diglyceride kinase beta;90 kDa diacylglycerol kinase;DAGK2;DGK-BETA
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DGKB-11954H | Recombinant Human DGKB, His-tagged | E.coli | Human | His | 30-140a.a. | |
| DGKB-1855R | Recombinant Rat DGKB Protein | Mammalian Cells | Rat | His |
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| DGKB-4543M | Recombinant Mouse DGKB Protein | Mammalian Cells | Mouse | His |
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| DGKB-6958HCL | Recombinant Human DGKB 293 Cell Lysate | HEK293 | Human | Non |
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| DGKB-6959HCL | Recombinant Human DGKB 293 Cell Lysate | HEK293 | Human | Non |
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| DGKB-1513R | Recombinant Rat DGKB Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| DGKB-1513R-B | Recombinant Rat DGKB Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| DGKB-2350M | Recombinant Mouse DGKB Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DGKB-2350M-B | Recombinant Mouse DGKB Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Dgkb-2535M | Recombinant Mouse Dgkb Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| DGKB-4338H | Recombinant Human DGKB Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
DGKB involved in several pathways and played different roles in them. We selected most pathways DGKB participated on our site, such as Choline metabolism in cancer,Effects of PIP2 hydrolysis,G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with DGKB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | ALDH2.2,LPIN3,AKR1B7,GK,LPIN2,DAK,AKR1B1L,MBOAT2B,ALDH9A1B,LCLAT1 |
| Gastrin-CREB signalling pathway via PKC and MAPK | ANXA1C,EDN1,TAE1,DGKQ,NMBB,NPS,GPR68,FFAR3,CASR,NMB |
| GPCR downstream signaling | RGS6,RGS7,RHOC,NMU,RAMP2,SST,PTH,ARHGAP4A,DRD3,MGLL |
| Glycerophospholipid metabolism | PLB1,PMT,CEPT1B,CHKB,GPCPD1,TESCA,DGKA,DGKZ,PHYKPL,PLD4 |
| Hemostasis | S100A10,SCG3,KIF5A,STXBP3A,DOCK8,APOER2,DOCK10,ATP2B1B,KIF3B,ABHD12 |
| Effects of PIP2 hydrolysis | ABHD12,PRKCHB,TRPC7,DGKA,ABHD6B,DGKG,TRPC3,DGKQ,TRPC6A,TAE1 |
| G alpha (q) signalling events | RASGRP2,EDN1,ANXA1,OPN4A,LPAR2B,GPR65,ANXA1A,KALRN,EDNRB,OPN4.1 |
| Choline metabolism in cancer | KRAS,DGKQ,WASF3,PDGFA,PPAP2C,HRAS,AKT2,SLC44A2,GPCPD1,PIK3R1 |
Protein Function
DGKB has several biochemical functions, for example, ATP binding,calcium ion binding,diacylglycerol kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DGKB itself. We selected most functions DGKB had, and list some proteins which have the same functions with DGKB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| diacylglycerol kinase activity | AGK,DGKA,DGKQ,DGKAA,DGKG,DGKE,DGKD,DGKZ,TAE1 |
| ATP binding | TOR1B,EPHA8,WEE1,CDK15,ABCG2D,TTBK1,RFK,ABCG3,TOR1L1,TRP53 |
| calcium ion binding | SPARC,PCDHB16,CDH15,NOX5,PPP3R1,PLA2G2A,PCDH1G11,SLC25A25B,SYT3,CDH2 |
Interacting Protein
DGKB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DGKB here. Most of them are supplied by our site. Hope this information will be useful for your research of DGKB.
KRT31;PCDHB5
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