DDX43
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Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -
Overview
The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. -
Synonyms
DDX43;DEAD (Asp-Glu-Ala-Asp) box polypeptide 43;probable ATP-dependent RNA helicase DDX43;cancer/testis antigen 13;CT13;DKFZp434H2114;HAGE;DDX43_HUMAN;DEAD box protein 43;DEAD box protein HAGE;Helical antigen;Probable ATP dependent RNA helicase DDX43;OTTHUMP00000016742;DEAD-box protein 43
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Wheat Germ
- Mammalian Cells
- In Vitro Cell Free System
- E.coli
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DDX43-2491H | Recombinant Human DDX43 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DDX43-6452Z | Recombinant Zebrafish DDX43 | Mammalian Cells | Zebrafish | His |
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| DDX43-457HCL | Recombinant Human DDX43 cell lysate | Human | Non |
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| DDX43-2605HF | Recombinant Full Length Human DDX43 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 648 amino acids |
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| DDX43-645H | Recombinant Human DDX43 protein, His-tagged | E.coli | Human | His | 264-648 aa |
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| Ddx43-6726M | Recombinant Mouse Ddx43 Protein (Met1-Ser268), N-His tagged | E.coli | Mouse | His | Met1-Ser268 |
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| Ddx43-6727M | Recombinant Mouse Ddx43 Protein (Mer1-Ser288), N-His tagged | E.coli | Mouse | His | Mer1-Ser288 |
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Involved Pathway
DDX43 involved in several pathways and played different roles in them. We selected most pathways DDX43 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DDX43 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX43 itself. We selected most functions DDX43 had, and list some proteins which have the same functions with DDX43. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | HNRNPC,KHDC1B,QK,RCAN3,CWC22,EMG1,PSMA6,ARHGEF28,ATXN1A,UPF1 |
| ATP binding | MYO1A,FIGNL1,EPHB6,SMYHC1,PRKCE,SKIV2L,ATAD2,ATP6V1AA,SMC3,OLA1 |
| ATP-dependent RNA helicase activity | DQX1,DHX15,EIF4A1,SKIV2L,DDX42,DDX23,DHX30,TMEM38A,G3BP1,EIF4A1A |
Interacting Protein
DDX43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX43 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX43.
Resources
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References
- Ambrosini, G; Khanin, R; et al. Overexpression of DDX43 Mediates MEK Inhibitor Resistance through RAS Upregulation in Uveal Melanoma Cells. MOLECULAR CANCER THERAPEUTICS 13:2073-2080(2014).
- Abdel-Fatah, TMA; McArdle, SEB; et al. HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer. BRITISH JOURNAL OF CANCER 110:2450-2461(2014).
