DCLRE1A
-
Official Full Name
DNA cross-link repair 1A -
Overview
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and;segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand;cross-links (Dronkert et al., 2000 (PubMed 10848582)). -
Synonyms
DCLRE1A;DNA cross-link repair 1A;DNA cross link repair 1A (PSO2 homolog, S. cerevisiae);DNA cross-link repair 1A protein;hSNM1;KIAA0086;PSO2;PSO2 homolog (S. cerevisiae);SNM1;hSNM1A;PSO2 homolog;SNM1 homolog A;DNA-crosslink repair gene SNM1;D
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DCLRE1A-11855H | Recombinant Human DCLRE1A, GST-tagged | E.coli | Human | GST | 690-1040a.a. | |
| DCLRE1A-1868C | Recombinant Chicken DCLRE1A | Mammalian Cells | Chicken | His |
|
|
| DCLRE1A-2738Z | Recombinant Zebrafish DCLRE1A | Mammalian Cells | Zebrafish | His |
|
|
| DCLRE1A-4364H | Recombinant Human DCLRE1A protein, His-tagged | E.coli | Human | His | 690-1040aa |
|
Involved Pathway
DCLRE1A involved in several pathways and played different roles in them. We selected most pathways DCLRE1A participated on our site, such as DNA Repair,Fanconi Anemia Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCLRE1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Repair | PPP4R2,CHEK2,RNF111,DTL,RAD18,RAD9,ELL,ALKBH2,RNF168,ALKBH3 |
| Fanconi Anemia Pathway | RMI2,MLH1,FANCI,RPA3,PALB2,POLI,ERCC1,FANCG,POLK,POLH |
Protein Function
DCLRE1A has several biochemical functions, for example, 5-3 exodeoxyribonuclease activity,damaged DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCLRE1A itself. We selected most functions DCLRE1A had, and list some proteins which have the same functions with DCLRE1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 5-3 exodeoxyribonuclease activity | EXO1,DCLRE1C |
| damaged DNA binding | APEX1,CREBBP,REV1,RPS3,TP53BP1,CRY2,RPA3,TP63,RPA2,TP53 |
Interacting Protein
DCLRE1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCLRE1A here. Most of them are supplied by our site. Hope this information will be useful for your research of DCLRE1A.
YWHAH
Resources
Related Services
Related Products
References
