DACH1

  • Official Full Name

    dachshund homolog 1

  • Overview

    This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    DACH1;dachshund homolog 1 (Drosophila);DACH, dachshund homolog (Drosophila);dachshund homolog 1;DACH;FLJ10138
Cat.# Product name Source (Host) Species Tag Protein Length Price
DACH1-2319H Recombinant Human DACH1 Protein, GST-tagged Wheat Germ Human GST
DACH1-27091TH Recombinant Human DACH1 Wheat Germ Human Non 109 amino acids
DACH1-4312C Recombinant Chicken DACH1 Mammalian Cells Chicken His
DACH1-7085HCL Recombinant Human DACH1 293 Cell Lysate HEK293 Human Non
DACH1-2311HF Recombinant Full Length Human DACH1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 558 amino acids

    Involved Pathway

    DACH1 involved in several pathways and played different roles in them. We selected most pathways DACH1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DACH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    DACH1 has several biochemical functions, for example, DNA binding,protein binding,transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly. Some of the functions are cooperated with other proteins, some of the functions could acted by DACH1 itself. We selected most functions DACH1 had, and list some proteins which have the same functions with DACH1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CRADD,XRN1,ATP1B1,SNX17,SSTR2,MYO5B,MRPL12,FCNA,ANKMY2,NME1
    transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding BCL11AA,ZFPM2A,TCF3,BCL11AB,SPI1,GATA1,NFIL3-2,AEBP2,JDP2,POU4F2
    DNA binding SPRTN,ZNF8,MXD4,EHF,MLF1,TAF15,ZNF32,DEDD2,LHX1A,VENT

    Interacting Protein

    DACH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DACH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DACH1.

    NAGK;SMAD4;NCOR1;SMAD3;SIN3A;UBE2I

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