CYP2S1

  • Official Full Name

    cytochrome P450, family 2, subfamily S, polypeptide 1

  • Overview

    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined.

  • Synonyms

    CYP2S1;cytochrome P450, family 2, subfamily S, polypeptide 1;cytochrome P450, subfamily IIS, polypeptide 1;cytochrome P450 2S1;CYPIIS1;cytochrome P540, subfamily IIS, polypeptide 1;cytochrome P450 family member predicted from ESTs

Recombinant Proteins

  • Mouse
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Flag
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CYP2S1-4201M Recombinant Mouse CYP2S1 Protein Mammalian Cells Mouse His
CYP2S1-7108HCL Recombinant Human CYP2S1 293 Cell Lysate HEK293 Human Non
CYP2S1-1451HFL Recombinant Full Length Human CYP2S1 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
CYP2S1-2150M Recombinant Mouse CYP2S1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CYP2S1-2150M-B Recombinant Mouse CYP2S1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Cyp2s1-2419M Recombinant Mouse Cyp2s1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
CYP2S1-704H Recombinant Human CYP2S1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
CYP2S1-704H-B Recombinant Human CYP2S1 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    CYP2S1 involved in several pathways and played different roles in them. We selected most pathways CYP2S1 participated on our site, such as Biological oxidations,CYP2E1 reactions,Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP2S1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of xenobiotics by cytochrome P450 ADH2-1,CYP2F1,ADH2-2,AKR1C2,PRKRA,AKR1C4,GSTK1
    Biological oxidations ADH4,CYP24A1,CYP27B1,CYP46A1,PRKRA,CYP4F11,AKR1A1,COMT,ACY3.1,DPEP2
    Miscellaneous substrates CYP2K18,CYP2K17,CYP2K6,CYP3C1,CYP3C4,CYP4F22,CYP2K16,CYP4F11,CYP2K19,CYP4B1
    CYP2E1 reactions CYP2A7,CYP2C19,CYP2Y3,CYP2A6,CYP2C8,CYP2B6,CYP2A13,CYP2C9,CYP2E1,CYP2F1
    Metabolic pathways ADH2-1,CYP4A10,PMM1,COX15,POLR2G,ACSL5,MTMR2,HYAL1,PIP5KL1,MTMR7A
    Metabolism STAB2,ATP5H,HS3ST6,CD320,GNG13A,APOA4B.2,VAPB,ELA2,ATP5S,SLC25A12
    Phase 1 - Functionalization of compounds CES1,CYP8B2,CYP2R1,CYP2W1,CYP2K17,ADH8B,CYP3C4,CYP3A7,CYP2U1,ADH8A
    Cytochrome P450 - arranged by substrate type CYP3C4,CYP2K22,CYP11B2,CYP2D6,CYP2AD3,CYP2A6,CYP27B1,CYP21A2,CYP19A1,CYP3A4

    Protein Function

    CYP2S1 has several biochemical functions, for example, arachidonic acid epoxygenase activity,aromatase activity,heme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP2S1 itself. We selected most functions CYP2S1 had, and list some proteins which have the same functions with CYP2S1. You can find most of the proteins on our site.

    Function Related Protein
    oxygen binding CYP2K6,HBE1,HBAE1,CYP2P7,HBZ,CYP1B1,CYP2J6,HBM,CYP2C37,CYP2AA12
    heme binding DUOX2,CYP2P10,CYP4V8,CYP2R1,HBD,CYP2P8,CAT,FECH,CYP4F18,CYP2J6
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen CYP2AA7,CYP2D26,CYP2P8,CYP2J6,CYP2K22,CYP2J2,CYP2V1,CYP2D6,CYP2C9,CYP2D9
    iron ion binding CYP26B1,CYP2AA8,CYP2F2,NOS1,CYP2P10,TYW1B,CYP2C19,CYP2A12,ALOX5,CYP21A1
    protein binding GBF1,VEGFA,NSG1,KRT1,DDB1,SCNN1G,LDHB,TIA1,NDE1,MED4
    steroid hydroxylase activity CYP2D9,CYP2J5,CYP2P6,CYP46A1.2,CYP2B6,CYP2K22,CYP2X8,CYP2D6,CYP2J6,CYP46A1.4
    arachidonic acid epoxygenase activity CYP2AA4,CYP2AD2,CYP2D10,CYP2AD3,CYP2AA12,CYP2A4,CYP2A6,CYP2N13,CYP2AA1,CYP2C8
    aromatase activity CYP2F1,CYP2J6,CYP2C55,CYP2C18,CYP1B1,CYP4A12A,CYP2D6,CYP3A5,CYP2A7,CYP2B19

    Interacting Protein

    CYP2S1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP2S1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP2S1.

    ADAMTSL4;ADAMTSL4

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