CYFIP1
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Official Full Name
cytoplasmic FMR1 interacting protein 1 -
Overview
Cytoplasmic FMR1-interacting protein 1 is a protein that in humans is encoded by the CYFIP1 gene. -
Synonyms
CYFIP1;cytoplasmic FMR1 interacting protein 1;cytoplasmic FMR1-interacting protein 1;cytoplasmic FMRP interacting protein 1;KIAA0068;P140SRA 1;selective hybridizing clone;SHYC;CY;CYFP1_HUMAN;p140sra-1;P140SRA1;Specifically Rac1 associated protein 1;Specifically Rac1-associated protein 1;SRA 1;Sra-1;SRA1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CYFIP1-12029Z | Recombinant Zebrafish CYFIP1 | Mammalian Cells | Zebrafish | His |
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| CYFIP1-2228H | Recombinant Human CYFIP1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CYFIP1-4137M | Recombinant Mouse CYFIP1 Protein | Mammalian Cells | Mouse | His |
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| CYFIP1-2121M | Recombinant Mouse CYFIP1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CYFIP1-2121M-B | Recombinant Mouse CYFIP1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
CYFIP1 involved in several pathways and played different roles in them. We selected most pathways CYFIP1 participated on our site, such as RNA transport,Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYFIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | EIF3HB,SIP1,CYFIP2,EIF4EBP3,TACC3,GEMIN7,SMN,NUP98,EIF4E1C,SUMO4 |
| Regulation of Actin Cytoskeleton | FGF19,GNG12A,PPP1CC,FGF6A,RAF1A,PIP5K1C,MYLK,ACTB2,PIK3CG,ITGB8 |
Protein Function
CYFIP1 has several biochemical functions, for example, contributes_to Rac GTPase binding,actin binding,profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYFIP1 itself. We selected most functions CYFIP1 had, and list some proteins which have the same functions with CYFIP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | LAMB3,HNF1B,PPP2R2A,MYC,MLC1,MYO7A,HCLS1,VAMP2,SIX2,FBLN1 |
| protein binding | VAV1,TSC22D4,SH2B3,PCGF5,BASP1,TRP53,PURA,NOTCH3,CAML,SNX10 |
| actin binding | SMTNL,DAG1,CAPZA2,PLECA,ACTN3B,FMNL2,INPPL1,RP2,PARVAB,XIRP1 |
| contributes_to Rac GTPase binding | WASF1,ABI2,BRK1,NCKAP1 |
| profilin binding | EVL,DIAP1,VASP,HTT,PCLO,WIPF1,FMNL1,RHOQ,DIAPH1,CTTN |
Interacting Protein
CYFIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYFIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYFIP1.
Eif4e;Fmr1;map1b_mouse_mrna;Pik3r1;Eif6;Rps6;FMR1;7-methyl-gtp
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References
- Abekhoukh, S; Bardoni, B; et al. CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome. FRONTIERS IN CELLULAR NEUROSCIENCE 8:-(2014).
- Bozdagi, O; Sakurai, T; et al. Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice. PLOS ONE 7:-(2012).
