CYBRD1
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Official Full Name
cytochrome b reductase 1 -
Overview
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. -
Synonyms
CYBRD1;cytochrome b reductase 1;DCYTB;ferric chelate reductase 3;FLJ23462;FRRS3;CYBR 1;CYBR1;CYBR1_HUMAN;CYBRD 1;DKFZp564E227;Duodenal cytochrome b;Ferric-chelate reductase 3
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- Xenopus laevis
- zebrafish
- Pongo Abelii
- Mus musculus
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CYBRD1 involved in several pathways and played different roles in them. We selected most pathways CYBRD1 participated on our site, such as Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYBRD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mineral absorption | MT1A,SLC26A6,CLCN2,MT1G,MT1,HMOX1,ATP1B2,ATP1A2,MT2,FTL |
Protein Function
CYBRD1 has several biochemical functions, for example, ferric-chelate reductase activity,metal ion binding,oxidoreductase activity, oxidizing metal ions. Some of the functions are cooperated with other proteins, some of the functions could acted by CYBRD1 itself. We selected most functions CYBRD1 had, and list some proteins which have the same functions with CYBRD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ferric-chelate reductase activity | FRRS1,CYB561 |
| protein binding | VAC14,TCTN2,NRIP3,TFF1,HMGA1,NINJ1,CCDC12,MOBKL1A,MUTYH,CLIC2 |
| metal ion binding | TOP2B,ZFY2,TIMP3,METAP2A,ZNF490,TRIM43B,PVALB6,RUNX1T1,PITPNM1,NRXN1A |
Interacting Protein
CYBRD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYBRD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYBRD1.
STX4;Flot1;PCDH7;FLNA;Rab5c;MYH9;Bmpr1a;IQGAP1;RAB7A;Tpm1;Actb;ACTR2;DBN1;Rmdn3;Flot2;Tsg101;Myh10
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References
- Kang, PT; Yun, J; et al. Design and Use of Peptide-Based Antibodies Decreasing Superoxide Production by Mitochondrial Complex I and Complex II. BIOPOLYMERS 96:207-221(2011).
- Ott, G; Plitzko, B; et al. Reduction of Sulfamethoxazole Hydroxylamine (SMX-HA) by the Mitochondrial Amidoxime Reducing Component (mARC). CHEMICAL RESEARCH IN TOXICOLOGY 27:1687-1695(2014).
