CYB5R4
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Official Full Name
cytochrome b5 reductase 4 -
Overview
NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5;reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 (PubMed 10611283)). -
Synonyms
CYB5R4;cytochrome b5 reductase 4;NADPH cytochrome B5 oxidoreductase , NCB5OR;b5+b5R;dJ676J13.1;b5b5r;C79736;cb5/cb5R;Cb5cb5r;Cytochrome b type NAD(P)H oxidoreductase;Flavohemoprotein b5+b5R;Flavohemoprotein b5/b5R;N terminal cytochrome b5 and cytochrome b5 oxidoreductase domain containing protein;N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein;NADPH cytochrome B5 oxidoreductase;NB5R4_HUMAN;NCB5OR;RP4 676J13.1;OTTHUMP00000016802;cytochrome b-type NAD(P)H oxidoreductase;RP4-676J13.1
Recombinant Proteins
- Rhesus macaque
- Human
- Zebrafish
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CYB5R4 involved in several pathways and played different roles in them. We selected most pathways CYB5R4 participated on our site, such as Amino sugar and nucleotide sugar metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYB5R4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amino sugar and nucleotide sugar metabolism | GMPPB,UXS1,HKDC1,CMASA,GALK1,PGM1,UGP2,CYB5R1,PGM3,GMPPAA |
Protein Function
CYB5R4 has several biochemical functions, for example, NAD(P)H oxidase activity,NOT NAD(P)H oxidase activity,cytochrome-b5 reductase activity, acting on NAD(P)H. Some of the functions are cooperated with other proteins, some of the functions could acted by CYB5R4 itself. We selected most functions CYB5R4 had, and list some proteins which have the same functions with CYB5R4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytochrome-b5 reductase activity, acting on NAD(P)H | NQO1,CYB5R1,CYB5RL,CYB5R3,POR,CYB5R2 |
| heme binding | CYP1A4,LPO,CYP4V2,PGRMC2,CYP2X10.2,HBB,CYP2A4,CYP4F12,CYP19A1,HBE |
| oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor | COX15 |
| NAD(P)H oxidase activity | AIFM1,KMO,NOX4,DUOX2,DERL3 |
| metal ion binding | ADCY1,PRKCHB,ZNF266,UQCRC2B,GLRX2,NUPL2,ATP13A5,SUMF1,MMP14B,MOB2 |
Interacting Protein
CYB5R4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYB5R4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYB5R4.
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