CXXC1
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Official Full Name
CXXC finger protein 1 -
Overview
Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate;gene expression (Carlone and Skalnik, 2001 (PubMed 11604496)). -
Synonyms
CXXC1;CXXC finger protein 1;CXXC finger 1 (PHD domain);cpG-binding protein;CFP1;CGBP;CpG binding protein;DNA binding protein with PHD finger and CXXC domain;hCGBP;HsT2645;PCCX1;PHF18;SPP1;ZCGPC1;zinc finger;CpG binding type containing 1;CX
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CXXC1-3305H | Recombinant Human CXXC1 protein, His-tagged | E.coli | Human | His | ||
| CXXC1-1118R | Recombinant Rhesus monkey CXXC1 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| CXXC1-2204H | Recombinant Human CXXC1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CXXC1-27242TH | Recombinant Human CXXC1, His-tagged | E.coli | Human | His | 250-632 a.a. |
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| CXXC1-7151HCL | Recombinant Human CXXC1 293 Cell Lysate | HEK293 | Human | Non |
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| CXXC1-2372HF | Recombinant Full Length Human CXXC1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 656 amino acids |
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| CXXC1-943R | Recombinant Rhesus Macaque CXXC1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| CXXC1-943R-B | Recombinant Rhesus Macaque CXXC1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
CXXC1 involved in several pathways and played different roles in them. We selected most pathways CXXC1 participated on our site, such as IRE1alpha activates chaperones,Metabolism of proteins,Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with CXXC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| XBP1(S) activates chaperone genes | HYOU1,DNAJB9,HDGF,C19orf10,CTDSP2,TPP1,KLHDC3,WIPI1,SEC63,KDELR3 |
| Unfolded Protein Response (UPR) | KLHDC3,HYOU1,SEC63,TPP1,WIPI1,KDELR3,CTDSP2,FKBP14,ASNA1,YY2 |
| IRE1alpha activates chaperones | DNAJB9,KDELR3,WIPI1,ADD1,ASNA1,SERP1,DDX11,FKBP14,SEC61B,KLHDC3 |
| Metabolism of proteins | ARSK,NEU3,EEF1B2,MAGT1,CTSG,STT3A,SUMF2,A4GNT,CNIH2,ADAMTSL4 |
Protein Function
CXXC1 has several biochemical functions, for example, core promoter proximal region sequence-specific DNA binding,contributes_to histone methyltransferase activity (H3-K4 specific),protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXXC1 itself. We selected most functions CXXC1 had, and list some proteins which have the same functions with CXXC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| core promoter proximal region sequence-specific DNA binding | DMRT2B,KLF4,DMRTC1C2,SP3,MIXL1,DMRT1,SMAD3,UHRF1,DMRT3A,SP3A |
| contributes_to histone methyltransferase activity (H3-K4 specific) | DPY30,DYDC2,DYDC1,ASH2L,RBBP5 |
| zinc ion binding | ASH1L,CRIP2,ADAMTS15,CA15C,MKRN2,TRIM15,AICDA,RNF144AB,TRIM37,ADAM33 |
| protein binding | C1S,GSG2,SCN5A,USP19,NOLC1,FOXP4,GPN1,RAMP2,BCAS2,RNF111 |
| unmethylated CpG binding | DNMT3B,DNMT3A,KDM2A,MLL1 |
Interacting Protein
CXXC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXXC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXXC1.
RBBP5;SETD1A;TP53;WDR5
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