CTSW
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Official Full Name
cathepsin W -
Overview
The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. -
Synonyms
CTSW;cathepsin W;cathepsin W (lymphopain);lymphopain;LYPN;OTTHUMP00000233962;OTTHUMP00000233963
Recombinant Proteins
- Human
- Mouse
- Rat
- Wheat Germ
- E.coli
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- His&T7
- His&GST
- His&Fc&Avi
- His&Myc
- N-His&C-Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CTSW-2119H | Recombinant Human CTSW Protein, GST-tagged | Wheat Germ | Human | GST |
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| CTSW-404H | Recombinant Human cathepsin W, His-tagged | E.coli | Human | His | 22-376 a.a. |
|
| CTSW-4063M | Recombinant Mouse CTSW Protein | Mammalian Cells | Mouse | His |
|
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| CTSW-8183H | Recombinant Human CTSW protein, His & T7-tagged | E.coli | Human | His&T7 | Ile22~Pro376 |
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| Ctsw-8184M | Recombinant Mouse Ctsw protein, His & T7-tagged | E.coli | Mouse | His&T7 | Asp22~Pro371 |
|
| Ctsw-1294R | Recombinant Rat Ctsw Protein, His&GST-tagged | E.coli | Rat | His&GST | Asp22-Pro371 |
|
| CTSW-1894H | Recombinant Human CTSW Protein (Ile22-Pro376), N-His tagged | E.coli | Human | His | Ile22-Pro376 |
|
| CTSW-2073M | Recombinant Mouse CTSW Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CTSW-2073M-B | Recombinant Mouse CTSW Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CTSW-2364HF | Recombinant Full Length Human CTSW Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 22-376 amino acids |
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| Ctsw-2768M | Recombinant Mouse Ctsw protein, His&Myc-tagged | E.coli | Mouse | His&Myc | 126-371aa |
|
| CTSW-4273H | Recombinant Human CTSW protein, His&Myc-tagged | E.coli | Human | N-His&C-Myc | 128-376aa |
|
Involved Pathway
CTSW involved in several pathways and played different roles in them. We selected most pathways CTSW participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTSW were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | NAGLU,HYAL1,CTSSA,ARSA,AP4M1,ATP6V0C,ENTPD4,LIPA,IGF2R,LAPTM4A |
Protein Function
CTSW has several biochemical functions, for example, cysteine-type endopeptidase activity,cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CTSW itself. We selected most functions CTSW had, and list some proteins which have the same functions with CTSW. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase activity | USP17L5,CASP14,USP6,USP19,TINAG,USP12,CTSO,USP17L2,USP3,PDIA3 |
| cysteine-type peptidase activity | SENP3A,ZRANB1B,SENP7B,DESI2,PIGK,BLMH,USP2A,CASP6L2,Ctsl,USP43 |
Interacting Protein
CTSW has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTSW here. Most of them are supplied by our site. Hope this information will be useful for your research of CTSW.
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References
- Hobolt-Pedersen, AS; Delaisse, JM; et al. Osteoclast Fusion is Based on Heterogeneity Between Fusion Partners. CALCIFIED TISSUE INTERNATIONAL 95:73-82(2014).
- Sandstrom, A; Andersson, R; et al. Serum proteome profiling of pancreatitis using recombinant antibody microarrays reveals disease-associated biomarker signatures. PROTEOMICS CLINICAL APPLICATIONS 6:486-496(2012).
