CTSO
-
Official Full Name
cathepsin O -
Overview
The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. -
Synonyms
CTSO;cathepsin O;CTSO1;OTTHUMP00000220879
Recombinant Proteins
- Human
- Chicken
- Mouse
- HEK293
- E.coli
- Wheat Germ
- Mammalian Cells
- Insect Cells
- In Vitro Cell Free System
- His
- His&T7
- GST
- Non
- His&Fc&Avi
- His&MBP
- His&Myc
- N-His&C-Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CTSO-5005H | Recombinant Human CTSO Protein, His-tagged | HEK293 | Human | His | Asp24-Val321 | |
| CTSO-1103H | Recombinant Human CTSO protein, His & T7-tagged | E.coli | Human | His&T7 | Arg111~Ser317 |
|
| CTSO-2117H | Recombinant Human CTSO Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| CTSO-2801C | Recombinant Chicken CTSO | Mammalian Cells | Chicken | His |
|
|
| CTSO-4059M | Recombinant Mouse CTSO Protein | Mammalian Cells | Mouse | His |
|
|
| CTSO-7190HCL | Recombinant Human CTSO 293 Cell Lysate | HEK293 | Human | Non |
|
|
| CTSO-2072M | Recombinant Mouse CTSO Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| CTSO-2072M-B | Recombinant Mouse CTSO Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| CTSO-2213H | Recombinant Human CTSO protein, MBP&His-tagged | Insect Cells | Human | His&MBP | 108-321aa |
|
| CTSO-2362HF | Recombinant Full Length Human CTSO Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 24-321 amino acids |
|
| CTSO-2765H | Recombinant Human CTSO protein, His&Myc-tagged | E.coli | Human | His&Myc | 108-321aa |
|
| CTSO-5006H | Recombinant Human CTSO Protein, His&Myc-tagged | HEK293 | Human | N-His&C-Myc | 108-321aa |
|
Involved Pathway
CTSO involved in several pathways and played different roles in them. We selected most pathways CTSO participated on our site, such as Adaptive Immune System,Immune System,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTSO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | SLAMF6,CTSC,TRIM38,IFIT10,ARIH1,ERAP1,LRR1,LRRFIP1,AMICA1,SH3RF1 |
| Lysosome | GNS,ATP6V0D2,CTSLA,Ctsl,ARSA,CTNS,AP3M2,AP3S1,M6PR,HYAL1 |
| MHC class II antigen presentation | CTSH,FAM49BA,KIFAP3,MGC174152,KIF26A,OSBPL1A,CTSC,CTSE,KIF3B,CTSLL |
| Adaptive Immune System | DCTN2,MGC174155,CD300A,DYNC1I2,AGO1,SH3RF1,TRIM9,RNF182,CD300LF,SIGLEC11 |
Protein Function
CTSO has several biochemical functions, for example, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CTSO itself. We selected most functions CTSO had, and list some proteins which have the same functions with CTSO. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase activity | CASP3A,CASP8,USP14,CTSM,CFLARA,PDIA3,CTSL.1,CTLA2B,CTSL1,CTSLA |
Interacting Protein
CTSO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTSO here. Most of them are supplied by our site. Hope this information will be useful for your research of CTSO.
hldE
Resources
Related Services
Related Products
References
- Pennypacker, BL; Chen, CM; et al. Inhibition of Cathepsin K Increases Modeling-Based Bone Formation, and Improves Cortical Dimension and Strength in Adult Ovariectomized Monkeys. JOURNAL OF BONE AND MINERAL RESEARCH 29:1847-1858(2014).
- Lerner, I; Zcharia, E; et al. Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice. CELLULAR AND MOLECULAR LIFE SCIENCES 71:2347-2357(2014).
