CTNND1
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Official Full Name
catenin (cadherin-associated protein), delta 1 -
Overview
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010] -
Synonyms
CTNND1;catenin (cadherin-associated protein), delta 1;CAS;p120;CTNND;P120CAS;P120CTN;p120(CAS);p120(CTN);catenin delta-1;p120 catenin;cadherin-associated Src substrate
Recombinant Proteins
- Rhesus macaque
- Human
- Mouse
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- His
- GST
- Non
- ABP
- Avi
- Fc
- DDK
- Myc
- Flag
Involved Pathway
CTNND1 involved in several pathways and played different roles in them. We selected most pathways CTNND1 participated on our site, such as Adherens junction,Adherens junctions interactions,Arf6 trafficking events, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTNND1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| E-cadherin signaling in the nascent adherens junction | ABI1,KLHL20,WASF2,NCKAP1 |
| E-cadherin signaling in keratinocytes | FMN1,CASR |
| Arf6 trafficking events | CLTC,EXOC6,PTBP3,SPAG9,EXOC5,CTNNA1,EDNRB,EXOC1,ADRB2,SCAMP2 |
| Cell junction organization | INADL,CDH13,CDH3,LIMS1,PARVB,CLDN23,CLDN20,DST,CADM2,CD151 |
| Cell-Cell communication | ITGB1B.1,CDH18A,DSCAMA,CDH18,FERMT2,CLDN4,NPHS1,CLDN7,CDH12,CDH4 |
| Adherens junctions interactions | CTNNA1,CDH12,JUPA,CADM2A,CDH6,CDH24,CDH13,CADM2,CDH10A,PVRL1A |
| Cell-cell junction organization | CADM2,CDH3,CDH10A,CDH24,CLDN23,JUPA,CDH5,CLDN7,CADM2A,ANG |
| Adherens junction | RHOAA,IGF1R,INSRA,CSNK2A2A,SMAD2,WASF3B,RAC2,PTPN6,SSX2IP,TGFBR1B |
Protein Function
CTNND1 has several biochemical functions, for example, cadherin binding,protein binding,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTNND1 itself. We selected most functions CTNND1 had, and list some proteins which have the same functions with CTNND1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | Artn,LRP6,EDA,HAO1,HSPA1B,IL28A,ICAM3,CD200,YES1,DHRS4 |
| cadherin binding | GNA13A,VCL,CTNNB1,CTNNAL1,FXYD5,NUMB,CDK5R1,CTNNA1,Fert2,CD46 |
| protein binding | LIMA1,PPP1R2P9,ZFP36,COX5B,RINT1,GATA1A,CENPK,RNF213,FAM82A2,CDK5 |
Interacting Protein
CTNND1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTNND1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTNND1.
PTPRJ;EGFR;PPAP2B;FRMD5
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References
- Li, GY; Yi, SM; et al. Identification of mutant genes with high-frequency, high-risk, and high-expression in lung adenocarcinoma. THORACIC CANCER 5:211-218(2014).
- Cain, RJ; Vanhaesebroeck, B; et al. The PI3K p110 alpha isoform regulates endothelial adherens junctions via Pyk2 and Rac1. JOURNAL OF CELL BIOLOGY 188:863-876(2010).
