CSRP3
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Official Full Name
cysteine and glycine-rich protein 3 (cardiac LIM protein) -
Overview
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene. This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. -
Synonyms
CSRP3;cysteine and glycine-rich protein 3 (cardiac LIM protein);cysteine and glycine-rich protein 3;CLP;CMD1M;MLP;cardiac;Muscle LIM protein;Cardiac LIM protein;CRP3;CSRP3_HUMAN;Cysteine rich protein 3;Cysteine-rich protein 3;LIM domain only 4;LIM domain protein;LMO4;OTTHUMP00000235874;cardiac LIM domain protein;LIM domain protein, cardiac;CMH12;MGC14488;MGC61993
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- Chicken
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- T7
- DDK
- Myc
- SUMO
- Non
- Avi
- Fc
- Flag
Involved Pathway
CSRP3 involved in several pathways and played different roles in them. We selected most pathways CSRP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CSRP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CSRP3 has several biochemical functions, for example, actinin binding,protein binding,structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by CSRP3 itself. We selected most functions CSRP3 had, and list some proteins which have the same functions with CSRP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of muscle | PDLIM3,JPH1,MYBPC3,MYL6B,TTN,TPM1,ACTN3,PLEC,ANKRD2,MYL3 |
| protein binding | GDAP2,HEBP2,RUSC1-AS1,MXD3,HDDC2,SART1,NFYC,UTP3,PIWIL1,HOXA3 |
| telethonin binding | KCNE1,TTN,BMP10,MYOZ2 |
| zinc ion binding | EWSR1,C6AST1,ZNRF1,PHC1,FHL5,MUL1,RARA,DTNBA,TXNDC17,RABIF |
| actinin binding | PDLIM5,PKD2,RELA,TTN,MICALL2,NFKB1,PROM1 |
Interacting Protein
CSRP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSRP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSRP3.
TCAP;MYOD1;MYOG;CFL2;s4s7m7_human;LIMS1;FHL1;RIN3;ACTN2
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