CPD
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Official Full Name
carboxypeptidase D -
Overview
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. -
Synonyms
CPD;carboxypeptidase D;gp180;Metallocarboxypeptidase D
Recombinant Proteins
- Rat
- Mouse
- Human
- Mammalian Cell
- HEK293
- E.coli
- Insect Cell
- His
- His&Fc&Avi
- His&Myc
- Fc&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CPD-1565R | Recombinant Rat CPD Protein | Mammalian Cell | Rat | His |
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| CPD-3835M | Recombinant Mouse CPD Protein | Mammalian Cell | Mouse | His |
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| CPD-1222R | Recombinant Rat CPD Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| CPD-1222R-B | Recombinant Rat CPD Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| CPD-1924M | Recombinant Mouse CPD Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CPD-1924M-B | Recombinant Mouse CPD Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CPD-2722H | Recombinant Human CPD protein, His&Myc-tagged | E.coli | Human | His&Myc | 383-461aa |
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| CPD-5899H | Recombinant Human CPD protein, His&Myc-tagged | Insect Cell | Human | His&Myc | 383-461aa |
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| CPD-5937H | Recombinant Human CPD protein, hFc-Myc-tagged | HEK293 | Human | Fc&Myc | 383-461aa |
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Involved Pathway
CPD involved in several pathways and played different roles in them. We selected most pathways CPD participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Golgi Associated Vesicle Biogenesis | GAK,TFR1B,HIP1R,NAPAB,AP1M2,SNX9,BLOC1S6,DTNBP1B,TPD52,CLINT1 |
| Vesicle-mediated transport | CLVS2,DTNBP1,FTH1A,NAPB,HYOU1,ARCN1,CNO,GJA8,BLOC1S4,TRAPPC6A |
| Clathrin derived vesicle budding | APPB,CTSZ,AP1M2,CLVS2,CLTC,CLTA,NAPAA,PICALMB,HIP1R,TFR1B |
| trans-Golgi Network Vesicle Budding | HIP1R,SH3D19,PLDN,PICALM,BLOC1S1,BLOC1S4,PUM1,YIPF6,TGOLN2,AP4B1 |
| Membrane Trafficking | LMAN2L,GJB7,PPP6R3,TMED10,HIP1RB,RALAB,SCFD1,GJA4,NAPAB,COPE |
Protein Function
CPD has several biochemical functions, for example, carboxypeptidase activity,hydrolase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPD itself. We selected most functions CPD had, and list some proteins which have the same functions with CPD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | YWHAB,AKAP5,EP300,WRN,UQCRC1,UQCRFS1,RIPK3,RANBP2,LAMB3,PTCH1 |
| zinc ion binding | TCF19,CA15C,UBR5,RORC,PHC2B,TRIM105,KDM2A,RNF141,MARCH11,MSL2 |
| metallopeptidase activity | C6AST1,ADAMTSL1,PGCP,ADAMTS1,C6AST3,AFG3L2,CNDP2,ENPEP,PAPPA2,PAPPAA |
| serine-type carboxypeptidase activity | DPP7,CPVL,CPM,SENP2,PRCP,CPN1,SCPEP1,CPZ,CPE,CPDB |
| metal ion binding | SUZ12A,CMC1,CYP8B1,PNLIP,CADPS,CYP51,HPD,ZFP146,ZDHHC6,DZIP1 |
| peptidase activity | PCSK5B,AGBL1,CTSBB,CAPN12,Ren1,PPPDE1,SPCS1,C3orf37,GZME,BAP1 |
| hydrolase activity | NPSN,KLK1B22,Ces2c,FAM105B,PRSS42,BPGM,PNPLA1,HDAC7,Aadacl3,PSMC1A |
| metallocarboxypeptidase activity | CPZ,CPB1,CPA5,CPA1,AGBL3,CPA3,CPE,CPB2,AGBL4,CPO |
| protein phosphatase 2A binding | FOXO1,RPS6KB1,STRN,MASTL,ARPP19,MAPT,ANKLE2,ENSAA,PPP2R2A,CTTNBP2NL |
Interacting Protein
CPD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPD here. Most of them are supplied by our site. Hope this information will be useful for your research of CPD.
Ankrd1;Ywhae;Clstn1
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References
- Guthrie, JW; Limmer, RT; et al. Simultaneous detection of ultraviolet B-induced DNA damage using capillary electrophoresis with laser-induced fluorescence. ANALYTICA CHIMICA ACTA 853:676-681(2015).
- Pastor, M; Esquisabel, A; et al. Cellulose acetate phthalate microparticles containing Vibrio cholerae: steps toward an oral cholera vaccine. JOURNAL OF DRUG TARGETING 22:478-487(2014).
