COL15A1
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Official Full Name
collagen, type XV, alpha 1 -
Overview
This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. -
Synonyms
COL15A1;collagen, type XV, alpha 1;collagen alpha-1(XV) chain;collagen type XV proteoglycan;collagen XV, alpha-1 polypeptide;FLJ38566
Recombinant Proteins
- Human
- Mouse
- HEK293
- E.coli
- Mammalian Cell
- HEK293T
- Mammalian cells
- HA
- Non
- His
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
COL15A1 involved in several pathways and played different roles in them. We selected most pathways COL15A1 participated on our site, such as Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL15A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein digestion and absorption | COL7A1,COL4A1,PRSS1,SLC3A1,SLC36A1,KCNE3,KCNK5,CELA2B,CELA2A,XPNPEP2 |
Protein Function
COL15A1 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COL15A1 itself. We selected most functions COL15A1 had, and list some proteins which have the same functions with COL15A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | PGM5,LELP1,JAG1,CLDN7,CLDN23,TUBA1A,EPB41L3B,LAMB2,VCLA,CYT1L |
Interacting Protein
COL15A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL15A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL15A1.
Ywhae
Resources
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References
- Dietrich-Ntoukas, T; Hofmann-Rummelt, C; et al. Comparative Analysis of the Basement Membrane Composition of the Human Limbus Epithelium and Amniotic Membrane Epithelium. CORNEA 31:564-569(2012).
- Cuesta, AM; Sanchez-Martin, D; et al. Improved stability of multivalent antibodies containing the human collagen XV trimerization domain. MABS 4:226-232(2012).
