COG4
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Official Full Name
component of oligomeric golgi complex 4 -
Overview
The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
COG4;component of oligomeric golgi complex 4;conserved oligomeric Golgi complex subunit 4;COD1;DKFZP586E1519;COG 4;COG complex subunit 4;Complexed with Dor1p;Conserved oligomeric Golgi complex protein 4;CDG2J
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COG4-1626H | Recombinant Human COG4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| COG4-2004C | Recombinant Chicken COG4 | Mammalian Cells | Chicken | His |
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| COG4-27221TH | Recombinant Human COG4, His-tagged | E.coli | Human | His | 1-478 a.a. |
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| COG4-3663Z | Recombinant Zebrafish COG4 | Mammalian Cells | Zebrafish | His |
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| COG4-2082HF | Recombinant Full Length Human COG4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 785 amino acids |
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Involved Pathway
COG4 involved in several pathways and played different roles in them. We selected most pathways COG4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with COG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
COG4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COG4 itself. We selected most functions COG4 had, and list some proteins which have the same functions with COG4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SHPRH,CRX,TLE4,IL17A,MATN3,FOXR2,NKX2-1,CLPP,KLHDC3,POLI |
Interacting Protein
COG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of COG4.
SCFD1;COG7;STX5;COG2;COG1
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References
- Gremillion, SK; Harris, SD; et al. Mutations in proteins of the Conserved Oligomeric Golgi Complex affect polarity, cell wall structure, and glycosylation in the filamentous fungus Aspergillus nidulans. FUNGAL GENETICS AND BIOLOGY 73:69-82(2014).
- Ha, JY; Pokrovskaya, ID; et al. Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:15762-15767(2014).
