CNOT6L
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Official Full Name
CCR4-NOT transcription complex, subunit 6-like -
Synonyms
CNOT6L;CCR4-NOT transcription complex, subunit 6-like;CCR4-NOT transcription complex subunit 6-like;DKFZp434K098;carbon catabolite repressor protein 4 homolog B;CCR4b
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- E.coli
- GST
- His
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CNOT6L involved in several pathways and played different roles in them. We selected most pathways CNOT6L participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNOT6L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | LSM7,WDR61,BTG3,EXOSC4,DCPS,BTG4,XRN1,PABPC1,DCP1B,EXOSC8 |
Protein Function
CNOT6L has several biochemical functions, for example, exonuclease activity,hydrolase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNOT6L itself. We selected most functions CNOT6L had, and list some proteins which have the same functions with CNOT6L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF843,ZNF485,SMAD4,SP8B,HE1B,KLF12,SCAPER,ZNF652,CTDSP2,ZFP14 |
| poly(A)-specific ribonuclease activity | PDE12,CNOT8,PARN,TOE1,PAN2,CNOT7,CNOT6 |
| exonuclease activity | REX1,RAD9,MEIOB,EXO5,XRN1,AEN,EXOSC9,WRN,ISG20,CNOT6 |
| hydrolase activity | ACP5B,ABHD2B,GM5136,DUSP28,INPP5KA,PSMB9A,PTPN11A,INPP5J,CTSL1B,KEX2 |
| nuclease activity | RAG1,EAR1,ENDOG,TDP2B,DOM3Z,RNASEKB,TMPPE,RNASEL2,EAR3,DNASE2A |
| protein binding | P4HA3,KRT20,B2M,SLC6A20B,ADCY6,IMMT,DCP1A,MRPL41,Siglec1,RAP2A |
Interacting Protein
CNOT6L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNOT6L here. Most of them are supplied by our site. Hope this information will be useful for your research of CNOT6L.
Cnot7;Cnot1;Cnot3;Rqcd1;Nanos2
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References
- Zhou, W; Thiery, JP; et al. Loss of Git2 induces epithelial-mesenchymal transition by miR146a-Cnot6L-controlled expression of Zeb1. JOURNAL OF CELL SCIENCE 126:2740-2746(2013).
- Wahle, E; Winkler, GS; et al. RNA decay machines: Deadenylation by the Ccr4-Not and Pan2-Pan3 complexes. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1829:561-570(2013).
