CMPK2

  • Official Full Name

    cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial

  • Overview

    This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal;differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this;gene.

  • Synonyms

    CMPK2;cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial;UMP-CMP kinase 2, mitochondrial;cytidylate kinase 2;TYKi;UMP CMPK2;UMP CMP kinase 2, mitochondrial;1200004E04Rik;Cytidine monophosphate (UMP CMP) kinase 2, mitochondrial;Mitochondrial UMP CMP kinase;OTTHUMP00000200305;Thymidine monophosphate kinase 2;TMPK2;mitochondrial UMP-CMP kinase;thymidylate kinase family LPS-inducible member;UMP-CMPK2

Recombinant Proteins

  • Human
  • Mouse
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • His
  • GST
  • Flag
  • Avi
  • Fc
  • DDK
  • Myc

    Involved Pathway

    CMPK2 involved in several pathways and played different roles in them. We selected most pathways CMPK2 participated on our site, such as CMP phosphorylation,Metabolic pathways,Pyrimidine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CMPK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways MTAP,ALP3,ALOX12E,URAD,EXTL3,PLA2G4D,POLR3GLB,TAT,ALDH6A1,UQCRQ
    Pyrimidine metabolism NME5,DCTPP1,NME1-NME2,POLR2F,NT5C1B-RDH14,NME4,POLR2EB,CMPK1,PNP,POLR3GLB
    UTP and CTP de novo biosynthesis NME6
    CMP phosphorylation NME6
    pyrimidine deoxyribonucleotide phosphorylation DTYMK
    superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis DUT

    Protein Function

    CMPK2 has several biochemical functions, for example, ATP binding,UMP kinase activity,cytidylate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CMPK2 itself. We selected most functions CMPK2 had, and list some proteins which have the same functions with CMPK2. You can find most of the proteins on our site.

    Function Related Protein
    cytidylate kinase activity AK8,CMPK,AK7,CMPK1
    nucleoside diphosphate kinase activity AK7,NME2,NME4,TXNDC3,NME5,NME8,NME2A,CMPK1,NME2B.1,AK4
    thymidylate kinase activity DTYMK
    ATP binding PI4KB,CBWD1,ABCB8,PI4K2A,MYO7A,MAP4K2,PAK2B,TMEM38A,RIOK2,MTPAP

    Interacting Protein

    CMPK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CMPK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CMPK2.

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