CLK3
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Official Full Name
CDC-like kinase 3 -
Overview
The cdc2-like kinase (CLK) family contains at least four highly conserved isoforms: CLK1, CLK2, CLK3 and CLK4. CLKs are dual specificity kinases that autophosphorylate on serine, threonine and tyrosine residues and phosphorylate exogenous substrates on se -
Synonyms
CLK3;CDC-like kinase 3;dual specificity protein kinase CLK3;PHCLK3;PHCLK3/152;FLJ22858
Recombinant Proteins
- Human
- Rat
- Chicken
- Mouse
- Insect Cells
- Mammalian Cell
- Insect Cell
- Wheat Germ
- Sf9 Insect Cell
- HEK293
- In Vitro Cell Free System
- Insect (sf21)
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
CLK3 involved in several pathways and played different roles in them. We selected most pathways CLK3 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA processing | HNRNPL,SFPQ,CELF4,RBM5,PTBP1,ADAM5,RBM12B1,PPM1G,PRPF4B,RBM12B2 |
Protein Function
CLK3 has several biochemical functions, for example, ATP binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLK3 itself. We selected most functions CLK3 had, and list some proteins which have the same functions with CLK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein serine/threonine kinase activity | MAP4K2,CAMK2D1,CDK1,BMPR1BA,AURKA,KALRN,VRK3,GM711,NEK7,CSNK1G2A |
| protein binding | USF2,GIP,OLFM2,HSF2,TADA2A,KCNRG,RPL5,RET,PFTK1,HIST1H3A |
| poly(A) RNA binding | TWF2,SUB1,MFAP1B,ESF1,PRPF31,HIST1H4M,HLTF,RPL19,ALKBH5,DDX24 |
| protein tyrosine kinase activity | FGFR3,Fert2,FGR,DYRK1B,EPHB2,JAK1,EGFRA,BMX,PTK7,MUSK |
| ATP binding | PSKH2,AARSD1,EHD3,PANK4,KIF5C,ACSF2,PAPD4,DNAJA1,FGFR2,SPATA5L1 |
| protein serine/threonine/tyrosine kinase activity | AURKC,AURKB,TESK1,MAP2K2,MAP2K1,DYRK1A,RPS6KB1,RPS6KA1,TTK,CLK2 |
Interacting Protein
CLK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLK3.
CLK2;SRPK2;RSRP1;YWHAG;386682
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