Clic6
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Official Full Name
chloride intracellular channel 6
Recombinant Proteins
- Rat
- Mouse
- Mus musculus
- Human
- Oryctolagus cuniculus (Rabbit)
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- His&Fc&Avi
Involved Pathway
Clic6 involved in several pathways and played different roles in them. We selected most pathways Clic6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Clic6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Clic6 has several biochemical functions, for example, D2 dopamine receptor binding,D3 dopamine receptor binding,D4 dopamine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Clic6 itself. We selected most functions Clic6 had, and list some proteins which have the same functions with Clic6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| D3 dopamine receptor binding | PALM,DRD1,DRD1A |
| protein C-terminus binding | FBLN1,PABPC1,SNTG1,MID1IP1,VGLL2,VGLL1,SIAH1,BCL10,ATF4,SAE1 |
| dopamine receptor binding | SLC9A3R1 |
| protein homodimerization activity | ACVR1,VPS4B,PRPS1,CHKA,BAXB,CRYBA1,PVRL2,UNC13A,TCF3A,ASNS |
| chloride channel activity | CLICA,GABRA2,SLC26A2,SLC26A3.2,SLC1A4,GABRA5,CFTR,GABRG2,SLC26A4,GABRA1 |
| voltage-gated ion channel activity | KCNK4,KCNIP4,CACNA1BA,CLIC5,KCNC1A,KCNB2,SCN12AB,KCNJ1A.6,TMEM109,KCNC2 |
| D2 dopamine receptor binding | DNM2,PPP1R9B |
Interacting Protein
Clic6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Clic6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Clic6.
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References
- Wahl, V; Vogler, S; et al. OSTEOPONTIN INHIBITS OSMOTIC SWELLING OF RETINAL GLIAL (MULLER) CELLS BY INDUCING RELEASE OF VEGF. NEUROSCIENCE 246:59-72(2013).
- Ohshiro, J; Yamamura, H; et al. The multiple expression of Ca2+-activated Cl- channels via homo- and hetero-dimer formation of TMEM16A splicing variants in murine portal vein. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 443:518-523(2014).
