CLIC5
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Official Full Name
chloride intracellular channel 5 -
Overview
This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded;protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair;cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance.;Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
CLIC5;chloride intracellular channel 5;chloride intracellular channel protein 5;MST130;MSTP130;FLJ90663
Recombinant Proteins
- Human
- Rat
- Mouse
- Mus musculus
- Bovine
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CLIC5 involved in several pathways and played different roles in them. We selected most pathways CLIC5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLIC5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CLIC5 has several biochemical functions, for example, chloride channel activity,NOT glutathione transferase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLIC5 itself. We selected most functions CLIC5 had, and list some proteins which have the same functions with CLIC5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated ion channel activity | SCN12AB,CACNG8A,SCN8AB,CLIC1,SCN4AB,PKD2,CATSPER2,CLIC2,KCNG4A,KCNC3A |
| chloride channel activity | CLIC4,CLCA1,CLCC1,ANO2,CLICA,SLC26A3.2,GABRG2,GABRP,TTYH2,CLIC6 |
| NOT glutathione transferase activity | CLIC2,CLIC3,CLIC1,ALOX5AP |
| protein binding | DLX2,KDR,CAMTA2,MRPL44,INTS3,ADAMTSL3,HMOX2,ACTN2,DNAJC15,CD74 |
Interacting Protein
CLIC5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLIC5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLIC5.
SRPK2;SRPK1;SRC;LAMTOR5;FN1;Fyn
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