CLDN9
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Official Full Name
claudin 9 -
Overview
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. -
Synonyms
CLDN9;claudin 9;claudin-9
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- HEK293
- Mammalian Cell
- HEK293T
- Insect Cell
- Mammalian cells
- E.coli expression system
- His
- Non
- Myc&DDK
- His&Strep
- His&Fc&Avi
- Flag
Involved Pathway
CLDN9 involved in several pathways and played different roles in them. We selected most pathways CLDN9 participated on our site, such as Cell adhesion molecules (CAMs),Tight junction,Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | MYH6,MYL12.2,CASK,RHOA,RRAS,EPB41L3B,MAGI3,MRAS,MYH15,CLDN18 |
| Leukocyte transendothelial migration | MYL12B,RHOA,ARHGAP5,PIK3R5,PIK3CG,CLDN14,MYL9,ACTG1,MYL2,PIK3R2 |
| Cell adhesion molecules (CAMs) | ITGB1B.2,CD80,NADL1.2,PTPRC,ITGA8,ITGAM,CLDN16,PVRL2,ALCAMA,NRCAM |
| Hepatitis C | PIK3CG,CLDN5,Ifna11,RAF1,CD81,TP53,MAPK11,OAS2,IFNA5,OSTN |
Protein Function
CLDN9 has several biochemical functions, for example, identical protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN9 itself. We selected most functions CLDN9 had, and list some proteins which have the same functions with CLDN9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | COMMD1,SOD2,DYNLT1,DAAM1,VCP,UBE4A,SELK,LEPR,SH2B2,BNIP2 |
| structural molecule activity | LAMA3,CLDN3,CYLC1,LCE3C,CLTCB,SPRR2D,KRT77,KRT97,CLDN14,KRT72-PS |
Interacting Protein
CLDN9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN9 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN9.
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