CLDN17
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Official Full Name
claudin 17 -
Overview
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. -
Synonyms
CLDN17;claudin 17;claudin-17;MGC126552;MGC126554;OTTHUMP00000101916;human CLDN17 gene for claudin-17
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Mus musculus
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- E.coli
- GST
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLDN17-1435H | Recombinant Human CLDN17 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CLDN17-3528M | Recombinant Mouse CLDN17 Protein | Mammalian Cells | Mouse | His |
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| CLDN17-6209Z | Recombinant Zebrafish CLDN17 | Mammalian Cells | Zebrafish | His |
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| CLDN17-7467HCL | Recombinant Human CLDN17 293 Cell Lysate | HEK293 | Human | Non |
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| CLDN17-1729M | Recombinant Mouse CLDN17 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| CLDN17-1729M-B | Recombinant Mouse CLDN17 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CLDN17-2046HF | Recombinant Full Length Human CLDN17 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 224 amino acids |
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| RFL189MF | Recombinant Full Length Mouse Claudin-17(Cldn17) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-224) |
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| RFL20807HF | Recombinant Full Length Human Claudin-17(Cldn17) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-224) |
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Involved Pathway
CLDN17 involved in several pathways and played different roles in them. We selected most pathways CLDN17 participated on our site, such as Cell adhesion molecules (CAMs),Tight junction,Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | PRKCDA,ACTB,CLDN22,PPP2R1A,CLDN19,MYH10,PRKCHA,RHOAC,CDC42,GNAIA |
| Leukocyte transendothelial migration | MMP9,ACTN4,VASP,CTNNA3,PLCG1,VAV3,CLDN2,ITGAM,CDC42,GNAI1 |
| Cell adhesion molecules (CAMs) | CLDN10A,HLA-DQB1,CLDNJ,ITGAL,ITGB1A,OCLN,CD2,NLGN3A,PVR,MADCAM1 |
| Hepatitis C | TRAF3,CXCL8,IRF7,CLDN1,PDPK1,GRB2,IKBKG,MAPK8,PIK3CD,DDX58 |
Protein Function
CLDN17 has several biochemical functions, for example, identical protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN17 itself. We selected most functions CLDN17 had, and list some proteins which have the same functions with CLDN17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | SHANK1,CLDN15,MSANTD3,AXIN1,CCL4,VWF,CLDN7,ALK,RASSF1,ADIPOQ |
| structural molecule activity | LLGL1,KRT35,INAA,CTNNA1,KRT19,SPRR1B,KRTAP3-2,DCTN3,COL15A1B,KRT6A |
Interacting Protein
CLDN17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN17 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN17.
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