CKS1B
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Official Full Name
CDC28 protein kinase regulatory subunit 1B -
Overview
CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. -
Synonyms
CKS1B;CDC28 protein kinase regulatory subunit 1B;CDC28 protein kinase 1B;cyclin-dependent kinases regulatory subunit 1;CKS1;ckshs1;CKS-1;PNAS-143;CDC28 protein kinase 1;CDC2-associated protein CKS1;cell division control protein CKS1;NB4 apoptos
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Chicken
- Rhesus macaque
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
CKS1B involved in several pathways and played different roles in them. We selected most pathways CKS1B participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Cyclin A:Cdk2-associated events at S phase entry, which may be useful for your reference. Also, other proteins which involved in the same pathway with CKS1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G1 Phase | CDKN2B,CDKN2C,CDKN2D,PIANP,E2F4 |
| Cyclin A:Cdk2-associated events at S phase entry | MYCA,CDK7 |
| Cyclin E associated events during G1/S transition | MYCA |
| G1/S Transition | DHFR,MYCA |
| Cell Cycle, Mitotic | CENPI,GORASP2,NUMA1,NIPBLA,TOP2A,NEK9,DCTN3,DBF4,VRK2,CNEP1R1 |
| FOXM1 transcription factor network | CENPA,AURKB,CENPB,FOXM1,CHEK2 |
| Cell cycle | CDC6,ACD,MLF1IP,ITGB3BP,DULLARD,E2F3,NDE1,SGOL1,OFD1,STAG2 |
| Cyclin D associated events in G1 | CDKN2C,CDK7,CDKN2B,E2F4,CDKN2D,PIANP |
Protein Function
CKS1B has several biochemical functions, for example, cyclin-dependent protein serine/threonine kinase regulator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CKS1B itself. We selected most functions CKS1B had, and list some proteins which have the same functions with CKS1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cyclin-dependent protein serine/threonine kinase regulator activity | CCNL1B,CCNL1,CCNY,FAM58A,CKS2,CDK4,CCNL2,CCNT2A,CCNL1A,CCNT2B |
| protein binding | PSKH1,NCOA3,SAP30L,TOP2A,ZNF3,GATA3,CBLB,FXN,GDI2,ROPN1L |
Interacting Protein
CKS1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CKS1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CKS1B.
CDK2;CDK1;SKP2
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