CHRD
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Official Full Name
chordin -
Overview
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined. -
Synonyms
CHRD;chordin;MGC133038
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CHRD-11201H | Recombinant Human CHRD, GST-tagged | E.coli | Human | GST | C-term-350a.a. | |
| CHRD-6539C | Recombinant Chicken CHRD | Mammalian Cell | Chicken | His |
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| CHRD-7524HCL | Recombinant Human CHRD 293 Cell Lysate | HEK293 | Human | Non |
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| CHRD-2256H | Recombinant Human CHRD Protein (Arg700-Leu918), His tagged | E.coli | Human | His | Arg700-Leu918 |
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| CHRD-308H | Recombinant Human CHRD Protein, His-tagged | E.coli | Human | His | Arg700~Leu918 |
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| Chrd-309M | Recombinant Mouse Chrd Protein, His-tagged | E.coli | Mouse | His | Ser422~Gly635 |
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Involved Pathway
CHRD involved in several pathways and played different roles in them. We selected most pathways CHRD participated on our site, such as TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TGF-beta signaling pathway | BMP4,ACVR1BA,TGFBR1B,SMAD2,RHOAC,MAPK3,SMAD7,PPP2R1A,RHOAA,RPS6KB2 |
Protein Function
CHRD has several biochemical functions, for example, cytokine binding,heparin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRD itself. We selected most functions CHRD had, and list some proteins which have the same functions with CHRD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| syndecan binding | SEMA5A,SDCBP,TNC,HPSE |
| protein binding | NUPL1,C6orf108,FIP1L1,PMS2,TBC1D10C,CCDC6,BCCIP,EPB41B,MYL6B,C6orf130 |
| cytokine binding | CRLF1,LIFR,NRP1,CD74,KIT,NOG,CXCR4,TNFRSF11A,IL31RA,IL17F |
| heparin binding | FSTL1,CFH,HRG,NRP1,FGF12,VTN,FGFR1A,NOV,ANG,WISP3 |
Interacting Protein
CHRD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRD here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRD.
MEOX2;PLSCR1;SPRY2;KRTAP5-9;OTX1
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